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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 76064
Country/Territory China
Category Gastroenterology and Hepatology
Manuscript Type Observational Study
Article Title Clinical implications of interleukins-31, 32, and 33 in gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Qing-Hua Liu, Ji-Wei Zhang, Lei Xia, Steven Wise, Brett David Hambly, Kun Tao and Shi-San Bao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81502030
Corresponding Author Shi-San Bao, MD, PhD, Academic Fellow, Department of Pathology, Tongren Hospital, No. 1111 Xianxia Road, Changning Distric, Shanghai 200336, China. bob.bao@sydney.edu.au
Key Words Diagnosis and therapy; Gastric cancer; Immune cell interactions; Interleukin-31; Interleukin 32; Interleukin-33
Core Tip Gastric cancer (GC) is one of the most common malignancies in China with a high morbidity and mortality. This study aimed to determine whether interleukin (IL)-31, IL-32, and IL-33 can be used as biomarkers for the detection of GC, via evaluating the correlations between their expression and clinicopathological parameters of GC patients. IL-31, IL-32, and IL-33 expression in GC was correlated with the severity of clinicopathological parameters. Circulating IL-33 was significantly low in GC patients. Our findings may provide new insights into the roles of IL-31, IL-32, and IL-33 in the carcinogenesis of GC.
Citation Liu QH, Zhang JW, Xia L, Wise S, Hambly BD, Tao K, Bao SS. Clinical implications of interleukins-31, 32, and 33 in gastric cancer. World J Gastrointest Oncol 2022; In press
Received
2022-02-28 23:24
Peer-Review Started
2022-02-28 23:26
To Make the First Decision
Return for Revision
2022-04-17 04:50
Revised
2022-04-21 14:14
Second Decision
2022-07-29 02:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-01 04:09
Articles in Press
2022-08-01 04:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-07-25 10:50
Typeset the Manuscript
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ping Yan
Reviewer Code 05194798, 05388315, and 05194798
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor Tian-Qi Wang
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 76064_Auto_Edited-LM.docx
Answering Reviewers 76064-Answering reviewers.pdf
Audio Core Tip 76064-Audio core tip.mp3
Biostatistics Review Certificate 76064-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 76064-Conflict-of-interest statement.pdf
Copyright License Agreement 76064-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 76064-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 76064-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 76064-Language certificate.pdf
Supplementary Material 76064-Supplementary material.pdf
Peer-review Report 76064-Peer-review(s).pdf
Scientific Misconduct Check 76064-Bing-Yan JP-2.png
Scientific Editor Work List 76064-Scientific editor work list.pdf