Publication Name	World Journal of Gastroenterology
Manuscript ID	76166
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Prevalence and factors associated with vitamin C deficiency in inflammatory bowel disease
Manuscript Source	Unsolicited Manuscript
All Author List	Benjamin Langan Gordon, Jonathan S Galati, Stevie Yang, Randy S Longman, Dana Lukin, Ellen J Scherl and Robert Battat
Funding Agency and Grant Number
Corresponding Author	Robert Battat, MD, Assistant Professor, Department of Gastroenterology and Hepatology, New York Presbyterian/Weill Cornell Medical Center, 1315 York Avenue, Mezzanine, New York, NY 10021, United States. rbattat20@icloud.com
Key Words	Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Vitamin C deficiency; Scurvy; Malnutrition
Core Tip	This study aimed to determine proportions and factors associated with vitamin C deficiency in inflammatory bowel disease (IBD) patients. In 301 patients, 21.6% had vitamin C deficiency, including 24.4% of Crohn’s disease and 16.0% of ulcerative colitis patients. Patients with elevated C-reactive protein (39.1% vs 16.9%) and fecal calprotectin (50.0% vs 20.0%) had higher proportions of deficiency compared to those without, as did patients with penetrating disease (36.2% vs 20.8%). This study provides the largest data on vitamin C deficiency in IBD, and demonstrates that deficiency is common in this population, particularly those with markers of active luminal or penetrating disease.
Citation	Gordon BL, Galati JS, Yang S, Longman RS, Lukin D, Scherl EJ, Battat R. Prevalence and factors associated with vitamin C deficiency in inflammatory bowel disease. World J Gastroenterol 2022; 28(33): 4834-4845

Received	2022-03-14 18:53
Peer-Review Started	2022-03-14 18:55
To Make the First Decision
Return for Revision	2022-05-09 07:35
Revised	2022-05-23 02:47
Second Decision	2022-08-03 02:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-06 22:39
Articles in Press	2022-08-06 22:39
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-08-25 01:10

ISSN	1007-9327 (print) and 2219-2840 (online)
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