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6/20/2022 10:19:41 PM | Browse: 65 | Download: 34
Publication Name World Journal of Stem Cells
Manuscript ID 76207
Country/Territory China
Category Dentistry, Oral Surgery and Medicine
Manuscript Type Review
Article Title Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications
Manuscript Source Invited Manuscript
All Author List Sheng-Meng Yuan, Xue-Ting Yang, Si-Yuan Zhang, Wei-Dong Tian and Bo Yang
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China U21A20369
Sichuan Science and Technology Program 2021YJ0147
Research and Develop Program, West China Hospital of Stomatology Sichuan University RD-02-202113
Corresponding Author Bo Yang, DDS, PhD, Academic Fellow, Chief Doctor, State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Engineering Research Center of Oral Translational Medicine, National Engineering Laboratory for Oral Regenerative Medicine, West China Hospital of Stomatology, Sichuan University, No. 14 3rd Section, Renmin South Road, Chengdu 610041, Sichuan Province, China. dr.yangbo@scu.edu.cn
Key Words Dental pulp stem cells; Cell injections; Modified cells; Cell sheets; Cell spheroids; Regeneration
Core Tip In this review, we aim to outline the present understanding of the potential application of dental pulp stem cells (DPSCs) and their derivatives in the field of regenerative medicine. DPSCs have different properties and regenerative potentials according to the age and health condition of the donor. For therapeutic applications, DPSCs can be administered through different methodologies, including by single injections and the transplantation of the cells and their derivatives with a support, as cell sheets or as cell spheroids. The underlying mechanisms of the regenerative potential of DPSCs and their derivatives may occur through direct regulation and immunomodulatory and paracrine effects.
Citation Yuan SM, Yang XT, Zhang SY, Tian WD, Yang B. Therapeutic potential of dental pulp stem cells and their derivatives: Insights from basic research toward clinical applications. World J Stem Cells 2022; In press
2022-03-14 15:59
Peer-Review Started
2022-03-14 16:01
To Make the First Decision
Return for Revision
2022-05-11 06:56
2022-05-25 07:45
Second Decision
2022-06-13 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-06-20 22:19
Articles in Press
2022-06-20 22:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Jia-Ru Fan
Reviewer Code 06187298, 05293115, 05234011, and 05489967
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 76207_Auto_Edited_LM.docx
Answering Reviewers 76207-Answering reviewers.pdf
Audio Core Tip 76207-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 76207-Conflict-of-interest statement.pdf
Copyright License Agreement 76207-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 76207-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 76207-Language certificate.pdf
Peer-review Report 76207-Peer-review(s).pdf
Scientific Misconduct Check 76207-Bing-Fan JR-2.png
Scientific Editor Work List 76207-Scientific editor work list.pdf