Publication Name	World Journal of Biological Chemistry
Manuscript ID	76252
Country	Poland

Category	Hematology
Manuscript Type	Basic Study
Article Title	Profiles of interferon-gamma and interleukin-2 in patients after allogeneic hematopoietic stem cell transplantation
Manuscript Source	Invited Manuscript
All Author List	Malwina Rybicka-Ramos, Mirosław Markiewicz, Aleksandra Suszka-Świtek, Ryszard Wiaderkiewicz, Sylwia Mizia, Monika Dzierżak-Mietła and Krzysztof Białas
Funding Agency and Grant Number
Corresponding Author	Malwina Rybicka-Ramos, MD, PhD, Doctor, Doctor, Department of Hematology, Specialist Hospital No. 1 in Bytom, 7 Zeromskiego Street, Bytom 41-902, Poland. malwina.rybicka@gmail.com
Key Words	Interleukin-2; Interferon-gamma; Cytokine profiles; Acute myeloid leukemia; Allogeneic hematopoietic stem cell transplantation; Acute graft-versus-host disease
Core Tip	This paper presents the profiles of interleukin-2 and interferon-gamma levels depending on the occurrence of acute graft-versus-host disease and infection complications after allogeneic hematopoietic stem cell transplantation (allo-HSCT). In this study, the cytokine levels were assessed in the early period after allo-HSCT (within the first 30 d after transplantation). Before, during, and after blood sampling for cytokine determination, cytokine-producing cells were not stimulated with mitogenic substances (lipopolysaccharide or phytohemagglutinin). Therefore, the obtained cytokine levels and their profiles may be regarded as those which reflect real values in patients who underwent allo-HSCT.
Citation	Rybicka-Ramos M, Markiewicz M, Suszka-Świtek A, Wiaderkiewicz R, Mizia S, Dzierżak-Mietła M, Białas K. Profiles of interferon-gamma and interleukin-2 in patients after allogeneic hematopoietic stem cell transplantation. World J Biol Chem 2022; 13(4): 72-82

Received	2022-03-08 21:20
Peer-Review Started	2022-03-08 21:23
To Make the First Decision
Return for Revision	2022-04-29 15:35
Revised	2022-05-11 17:42
Second Decision	2022-09-21 03:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-09-21 23:54
Articles in Press	2022-09-21 23:54
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-09-16 23:58
Typeset the Manuscript	2022-09-23 10:32

ISSN	1949-8454 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com