Publication Name	World Journal of Virology
Manuscript ID	76352
Country	India

Category	Virology
Manuscript Type	Review
Article Title	Association of COVID-19 with hepatic metabolic dysfunction
Manuscript Source	Invited Manuscript
All Author List	Ramesh Kumar, Vijay Kumar, Rahul Arya, Utpal Anand and Rajeev Nayan Priyadarshi
Funding Agency and Grant Number
Corresponding Author	Ramesh Kumar, MD, Associate Professor, Department of Gastroenterology, All India Institute of Medical Sciences, Patna, Phulwari Sharif, Patna 801507, Bihar, India. docrameshkr@gmail.com
Key Words	COVID-19; Coronavirus; Metabolism; Metabolic syndrome; Metabolic inflammation; Hepatic dysfunction
Core Tip	In coronavirus disease 2019 (COVID-19) patients, the virus induces a complex viral-host interaction that leads to metabolic reprogramming, altered immunological responses, and a variety of clinical consequences. In metabolomic and lipidomic studies, a variety of alterations in amino acids, lipids, carbohydrates, and energy metabolism have been identified in such patients. The liver is the primary metabolic organ; thus, these metabolic alterations may have a major impact on patients with liver diseases and metabolic comorbidities that are common in COVID-19 patients. Therefore, this review article discusses the pathophysiological aspects and clinical implications of metabolic dysfunction in COVID-19 patients with a focus on the liver.
Citation	Kumar R, Kumar V, Arya R, Anand U, Priyadarshi RN. Association of COVID-19 with Hepatic Metabolic Dysfunction. World J Virol 2022; 11(5): 237-251

Received	2022-03-13 10:04
Peer-Review Started	2022-03-13 10:06
To Make the First Decision
Return for Revision	2022-04-13 11:41
Revised	2022-04-25 11:00
Second Decision	2022-06-17 03:04
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-06-20 17:34
Articles in Press	2022-06-20 17:34
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-07-25 09:06
Typeset the Manuscript	2022-09-16 05:50

ISSN	2220-3249 (online)
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