Publication Name	World Journal of Stem Cells
Manuscript ID	76487
Country	Italy

Category	Medical Ethics
Manuscript Type	Opinion Review
Article Title	Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles
Manuscript Source	Invited Manuscript
All Author List	Martina Padovano, Matteo Scopetti, Federico Manetti, Donato Morena, Davide Radaelli, Stefano D'Errico, Nicola Di Fazio, Paola Frati and Vittorio Fineschi
Funding Agency and Grant Number
Corresponding Author	Vittorio Fineschi, MD, PhD, N/A, Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336, Rome 00185, Italy. vittorio.fineschi@uniroma1.it
Key Words	Pancreas transplantation; Multi-organ transplants; Stem cell therapy; Ethical principles
Core Tip	Recent research in pancreatic transplantation is involving many branches of medicine. The objective is represented by the achievement of euglycemia and the anatomo-functional restoration of the β-cells, avoiding the exogenous insulin administration. Transplantation of the pancreas or pancreatic islets (eventually associated with renal transplantation) and stem cell therapy constitute the new frontiers in this field. However, such rapid scientific growth must be followed by an extensive discussion on the ethical implications to make experimental and clinical practices adequate and sustainable.
Citation	Padovano M, Scopetti M, Manetti F, Morena D, Radaelli D, D'Errico S, Di Fazio N, Frati P, Fineschi V. Pancreatic transplant surgery and stem cell therapy: Finding the balance between therapeutic advances and ethical principles. World J Stem Cells 2022; 14(8): 577-586

Received	2022-03-18 17:02
Peer-Review Started	2022-03-18 17:04
To Make the First Decision
Return for Revision	2022-05-11 06:51
Revised	2022-05-24 17:13
Second Decision	2022-07-25 07:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-07-31 20:45
Articles in Press	2022-07-31 20:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-07-20 23:22
Typeset the Manuscript	2022-08-22 01:07

ISSN	1948-0210 (online)
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