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8/6/2022 8:19:50 PM | Browse: 59 | Download: 142
Publication Name World Journal of Clinical Cases
Manuscript ID 76792
Country/Territory China
Category Biochemistry & Molecular Biology
Manuscript Type Letter to the Editor
Article Title Glucose substrate in the hydrogen breath test for gut microbiota determination: A recommended noninvasive test
Manuscript Source Unsolicited Manuscript
All Author List Qi-Qi Xie, Jia-Feng Wang, Yang-Fen Zhang, Dong-Hui Xu, Bo Zhou, Ting-Hui Li and Zhi-Peng Li
Funding Agency and Grant Number
Corresponding Author Zhi-Peng Li, Doctor, MM, Attending Doctor, Surgeon, Teacher, School of medicine, Taizhou University, No. 1139, Shifu Avenue, Jiaojiang District, Taizhou, Zhejiang, P. R. China, Taizhou 318000, China. lzpzhonghong@126.com
Key Words Glucose; Hydrogen breath test; Lactulose; Liver cirrhosis; Small intestinal bacterial overgrowth
Core Tip The sensitivity of the hydrogen breath test is higher with glucose than lactulose as the substrate. We recommend using the hydrogen breath test in this experiment for measuring intestinal flora but replacing the test substrate with glucose. We recommend that the authors clarify the relation and concept of small intestinal bacterial overgrowth (SIBO) and gut dysbiosis. When exploring the relationship between gut dysbiosis and SIBO in cirrhosis, the etiology of SIBO should be considered. After estimating the sample size, we determined that the sample size included in the experiment was small and should be expanded.
Citation Xie QQ, Wang JF, Zhang YF, Xu DH, Zhou B, Li TH, Li ZP. Glucose substrate in the hydrogen breath test for gut microbiota determination: A recommended noninvasive test. World J Clin Cases 2022; 10(26): 9536-9538
Received
2022-03-31 01:47
Peer-Review Started
2022-03-31 01:50
To Make the First Decision
Return for Revision
2022-05-29 06:33
Revised
2022-06-06 11:56
Second Decision
2022-08-03 02:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-06 20:19
Articles in Press
2022-08-06 20:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-07-27 06:58
Typeset the Manuscript
2022-08-22 10:16
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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