Publication Name	World Journal of Stem Cells
Manuscript ID	76874
Country	Spain

Category	Cell Biology
Manuscript Type	Minireviews
Article Title	Metabolic determinants of stemness in medulloblastoma
Manuscript Source	Invited Manuscript
All Author List	Paula Martín-Rubio, Pilar Espiau-Romera, Alba Royo-Garcia, Laia Caja and Patricia Sancho
Funding Agency and Grant Number	Funding Agency Grant Number Instituto de Salud Carlos III- Miguel Servet Fellowship CP16/00121 Instituto de Salud Carlos III-pFIS Fellowship FI21/00031 Aspanoa IV Grant (2021) Magnus Bergvalls Stiftelse 2021-04284
Corresponding Author	Patricia Sancho, PhD, Senior Researcher, Hospital Universitario Miguel Servet, IIS Aragón, 1-3 Avda Isabel la Católica, Zaragoza 50009, Spain. psancho@iisaragon.es
Key Words	Medulloblastoma; Cancer stem cells; Stemness; Metabolism; Glycolysis; Lipids
Core Tip	Considering the profound cellular metabolism rewiring associated with the tumorigenesis process, metabolic targeting for cancer treatment has gained a lot of attention in the last years. Interestingly, increasing evidence indicates that cancer stem cells (CSCs) show unique metabolic features within tumours. A deeper understanding of the metabolic vulnerabilities of medulloblastoma (MB) and MB-CSCs would accelerate the design of novel therapeutic strategies with the aim of improving the survival of paediatric patients suffering this disease.
Citation	Martín-Rubio P, Espiau-Romera P, Royo-Garcia A, Caja L, Sancho P. Metabolic determinants of stemness in medulloblastoma. World J Stem Cells 2022; 14(8): 587-598

Received	2022-04-07 05:46
Peer-Review Started	2022-04-07 05:49
To Make the First Decision
Return for Revision	2022-05-11 06:40
Revised	2022-05-26 13:25
Second Decision	2022-07-29 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-01 05:02
Articles in Press	2022-08-01 05:02
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-08-07 06:49
Typeset the Manuscript	2022-08-22 01:08

ISSN	1948-0210 (online)
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