Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	77084
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Development of an innovative nomogram of risk factors to predict postoperative recurrence of gastrointestinal stromal tumors
Manuscript Source	Unsolicited Manuscript
All Author List	Shi-Hao Guan, Qiong Wang, Xiao-Ming Ma, Wen-Jie Qiao, Ming-Zheng Li, Ming-Gui Lai and Cheng Wang
Funding Agency and Grant Number
Corresponding Author	Cheng Wang, MM, Chief Doctor, Professor, Department of Gastrointestinal Tumor Surgery, The Affiliated Hospital of Qinghai University, No. 29 Tongren Road, Xining 810001, Qinghai Province, China. cheng_wang_vip@163.com
Key Words	Gastrointestinal stromal tumors; Recurrence; Clinicopathological; Predictors; Nomogram
Core Tip	This is a retrospective study to explore the risk factors for gastrointestinal stromal tumors recurrence after surgery. The nomogram included tumor site, lesion size, mitotic rate/50 high power fields, Ki-67 index, intracranial necrosis, and age as predictors. The model presented perfect discrimination with a reliable index of concordance (C-index) of 0.836 (95%CI: 0.712-0.960), and a high C-index value of 0.714 was also confirmed by interval validation. The area under the curve value of this prediction nomogram was 0.704, indicating good predictive value. Decision curve analysis showed that the predicting recurrence nomogram was clinically feasible.
Citation	Guan SH, Wang Q, Ma XM, Qiao WJ, Li MZ, Lai MG, Wang C. Development of an innovative nomogram of risk factors to predict postoperative recurrence of gastrointestinal stromal tumors. World J Gastrointest Surg 2022; 14(9): 940-949

Received	2022-04-14 12:08
Peer-Review Started	2022-04-14 12:10
To Make the First Decision
Return for Revision	2022-06-12 16:03
Revised	2022-07-02 08:55
Second Decision	2022-08-03 02:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-08-07 16:29
Articles in Press	2022-08-07 16:29
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-16 08:00

ISSN	1948-9366 (online)
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