Publication Name	World Journal of Clinical Infectious Diseases
Manuscript ID	77094
Country	United States

Category	Infectious Diseases
Manuscript Type	Retrospective Cohort Study
Article Title	Clinical significance of anti-nucleocapsid-IgG sero-positivity in SARS-CoV-2 infection in hospitalized patients in North Dakota
Manuscript Source	Unsolicited Manuscript
All Author List	Bakir Dzananovic, Mark Williamson, Casmiar Nwaigwe and Chittaranjan Routray
Funding Agency and Grant Number
Corresponding Author	Chittaranjan Routray, MD, Clinical Assistant Professor (Honorary), Family Medicine, University of North Dakota School of Medicine and Health Sciences, Minot, ND 58701, United States. routrayc@gmail.com
Key Words	COVID-19; SARS-CoV-2 IgG-N; Anti-nucleocapsid IgG; Cytokines
Core Tip	We intended to study an immunologic marker to predict the need for advanced oxygen supplement system and clinical outcome in order to support our hospital crisis management system during the peak of the pandemic. Our study demonstrated that presence of anti-nucleocapsid-IgG (IgG-N) against severe acute respiratory syndrome coronavirus 2 infection had no impact on the clinical outcome or disease severity in hospitalized coronavirus disease 2019 (COVID-19) patients. We did not find a correlation of statistical significance to use IgG-N as a biomarker to predict clinical outcome in COVID-19 patients admitted to a community hospital in North Dakota.
Citation	Dzananovic B, Williamson M, Nwaigwe C, Routray C. Clinical significance of anti-nucleocapsid-IgG sero-positivity in SARS-CoV-2 infection in hospitalized patients in North Dakota. World J Clin Infect Dis 2022; 12(2): 50-60

Received	2022-06-18 04:07
Peer-Review Started	2022-06-18 04:09
To Make the First Decision
Return for Revision	2022-07-14 08:41
Revised	2022-08-02 05:13
Second Decision	2022-09-20 03:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-09-21 22:20
Articles in Press	2022-09-21 22:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-09-25 12:53

ISSN	2220-3176 (online)
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