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Publication Name World Journal of Gastroenterology
Manuscript ID 77470
Country/Territory United States
Category Gastroenterology and Hepatology
Manuscript Type Meta-Analysis
Article Title Use of shear wave elastography for the diagnosis and follow-up of biliary atresia: A meta-analysis
Manuscript Source Unsolicited Manuscript
All Author List Ellen S Wagner, Hussien Ahmed H Abdelgawad, Meghan Landry, Belal Asfour, Mark B Slidell and Ruba Azzam
Funding Agency and Grant Number
Corresponding Author Ruba Azzam, MD, Associate Professor, Pediatric Gastroenterology, Hepatology, and Nutrition, The University of Chicago Medicine, Comer Children’ s Hospital, 5841 S Maryland Ave MC 4065, Chicago, IL 60637, United States. razzam@peds.bsd.uchicago.edu
Key Words Biliary atresia; Cholestasis; Hepatic portoenterostomy; Fibrosis; Esophageal and gastric varices; Elasticity imaging techniques
Core Tip Ultrasound elastography is an emerging, non-invasive imaging modality to detect organ stiffness. It may be a useful tool in biliary atresia (BA) diagnosis and post-Kasai fibrosis surveillance. In a meta-analysis of twenty existing studies (eleven for diagnosis and nine for follow-up), this paper shows that mean liver stiffness is significantly higher in BA patients compared to non-BA patients at time of diagnosis. Post-Kasai, elastography can differentiate between early and advanced fibrosis as well as help to discern the presence or absence of varices. While there are limitations to this analysis, elastography shows great promise for its utility as a non-invasive modality for BA patients.
Citation Wagner ES, Abdelgawad HAH, Landry M, Asfour B, Slidell MB, Azzam R. Use of shear wave elastography for the diagnosis and follow-up of biliary atresia: A meta-analysis. World J Gastroenterol 2022; In press
Received
2022-05-01 22:25
Peer-Review Started
2022-05-01 22:28
To Make the First Decision
Return for Revision
2022-06-19 05:25
Revised
2022-07-10 21:22
Second Decision
2022-07-29 02:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-08-01 03:13
Articles in Press
2022-08-01 03:13
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Yu-Lu Chen
Reviewer Code 05088164, 04364230, and 03260869
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor
Responsible Production Editor
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma
Manuscript File 77470_Auto_Edited-LM.docx
Answering Reviewers 77470-Answering reviewers.pdf
Audio Core Tip 77470-Audio core tip.m4a
Biostatistics Review Certificate 77470-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 77470-Conflict-of-interest statement.pdf
Copyright License Agreement 77470-Copyright license agreement.pdf
Supplementary Material 77470-Supplementary material.pdf
Peer-review Report 77470-Peer-review(s).pdf
Scientific Misconduct Check 77470-Bing-Chen YL-2.png
Scientific Editor Work List 77470-Scientific editor work list.pdf