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Publication Name World Journal of Clinical Cases
Manuscript ID 78500
Country Türkiye
Category Endocrinology & Metabolism
Manuscript Type Review
Article Title Endocrine disruptor chemicals as obesogen and diabetogen: Clinical and mechanistic evidence
Manuscript Source Invited Manuscript
All Author List Niyazi Emre Kurşunoğlu and Banu Pinar Sarer Yurekli
Funding Agency and Grant Number
Corresponding Author Banu Pinar Sarer Yurekli, MD, Associate Professor, Department of Endocrinology, Ege University School of Medicine, Ankara Street Bornova, İzmir 35100, Türkiye. bsareryurekli@yahoo.com
Key Words Endocrine disruptors; Adipogenesis; Obesity; Diabetes mellitus
Core Tip An exogenous chemical, or mixture of chemicals, that interferes with any aspect of hormone action was defined as Endocrine-Disrupting Chemicals (EDCs). Obesogens can promote obesity by increasing the number of adipocytes and fat storage in existing adipocytes, changing the calories burned at rest, changing the energy balance, and finally regulating satiety. Besides the obesogenic effect, EDCs can cause type 2 diabetes mellitus through alteration in ß cell function and morphology and insulin resistance. In this review, we provide clinical and mechanistic evidence regarding EDCs as obesogen and diabetogen.
Citation Kurşunoğlu NE, Sarer Yurekli BP. Endocrine disruptor chemicals as obesogen and diabetogen: Clinical and mechanistic evidence. World J Clin Cases 2022; 10(31): 11226-11239
Received
2022-06-29 21:23
Peer-Review Started
2022-06-29 21:27
To Make the First Decision
Return for Revision
2022-08-02 22:06
Revised
2022-08-19 15:49
Second Decision
2022-09-26 03:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-09-27 01:01
Articles in Press
2022-09-27 01:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-10-17 14:06
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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