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11/23/2022 3:00:29 AM | Browse: 61 | Download: 41
Publication Name World Journal of Cardiology
Manuscript ID 79843
Country/Territory United States
Category Cardiac & Cardiovascular Systems
Manuscript Type Case Report
Article Title Early and aggressive presentation of wild-type transthyretin amyloid cardiomyopathy: A case report
Manuscript Source Unsolicited Manuscript
All Author List Ilham Boda, Hassan Farhoud, Tarun Dalia, Amandeep Goyal, Zubair Shah and Andrija Vidic
Funding Agency and Grant Number
Corresponding Author Andrija Vidic, DO, N/A, Department of Cardiovascular Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, United States. avidic@kumc.edu
Key Words Wild-type; Transthyretin; Amyloidosis; Young; Heart failure; Heart transplant; Case report
Core Tip Wild-type transthyretin amyloidosis (ATTRwt) continues to be an underdiagnosed condition. Although rare in patients under 60 years of age, physicians should include the condition in their differential as early diagnosis and early management can impact patient outcomes. Physicians should be aware of the findings on non-invasive testing that supports ATTRwt. Classically on echocardiogram, cardiac amyloidosis can present as thickened ventricular walls, small lehigh valley chamber, biatrial enlargement, apical sparing on longitudinal strain and signs of elevated filling pressures and restrictive diastolic physiology (increased E/A ratio, E/e’ and reduced mitral annular tissue velocities). Cardiac magnetic resonance imaging classically shows late gadolinium enhancement. A technetium pyrophosphate study shows an increased heart-to-contralateral ratio and increased Perugini visual grade.
Citation Boda I, Farhoud H, Dalia T, Goyal A, Shah Z, Vidic A. Early and aggressive presentation of wild-type transthyretin amyloid cardiomyopathy: A case report. World J Cardiol 2022; 14(12): 657-664
2022-09-08 23:10
Peer-Review Started
2022-09-08 23:11
To Make the First Decision
Return for Revision
2022-10-13 01:20
2022-11-03 20:05
Second Decision
2022-11-18 04:15
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-11-23 03:00
Articles in Press
2022-11-23 03:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-11-30 07:36
ISSN 1949-8462 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Li-Li Wang
Reviewer Code 02446694, 03257640, and 02446694
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor Hua-Ge Yu
Responsible Production Editor Hua-Ge Yu
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma