Publication Name	World Journal of Gastroenterology
Manuscript ID	79950
Country	China

Category	Virology
Manuscript Type	Minireviews
Article Title	Liver injury in COVID-19: A minireview
Manuscript Source	Invited Manuscript
All Author List	Wen-Shu Hu, Fang-Ying Jiang, Wen Shu, Rong Zhao, Ji-Min Cao and De-Ping Wang
Funding Agency and Grant Number	Funding Agency Grant Number Key Medical Science and Technology Program of Shanxi Province 2020XM01 Shanxi “1331” Project Quality and Efficiency Improvement Plan 1331KFC Applied Basic Research Program of Shanxi Province 202103021224234 National Natural Science foundation of China 82170523
Corresponding Author	De-Ping Wang, PhD, Lecturer, Department of Physiology, Shanxi Medical University, No. 56 Xinjian Nan Road, Taiyuan 030001, Shanxi Province, China. wangdeping@sxmu.edu.cn
Key Words	Liver; SARS-CoV-2; Angiotensin-converting enzyme 2; Transmembrane serine protease 2; Chronic liver disease
Core Tip	The global pandemic of coronavirus disease 2019 (COVID-19) has imposed a great threat to human health and become a medical and social challenge. Although severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) mainly affects the respiratory tract, it also frequently damages the liver especially in severe and critical cases. Direct hepatotoxicity of SARS-CoV-2, or indirect hepatic injury caused by immune overactivation and systemic inflammation, drug-induced injury, ischemia/reperfusion and hypoxia/reoxygenation injuries, and worsening of preexisting liver diseases, are potential contributing factors to liver damage in COVID-19.
Citation	Hu WS, Jiang FY, Shu W, Zhao R, Cao JM, Wang DP. Liver injury in COVID-19: A minireview. World J Gastroenterol 2022; 28(47): 6716-6731

Received	2022-09-12 16:15
Peer-Review Started	2022-09-12 16:16
To Make the First Decision
Return for Revision	2022-10-19 20:05
Revised	2022-11-02 06:34
Second Decision	2022-11-23 03:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-11-23 06:49
Articles in Press	2022-11-23 06:49
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-11-16 12:15
Typeset the Manuscript	2022-11-28 02:54

ISSN	1007-9327 (print) and 2219-2840 (online)
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