BPG is committed to discovery and dissemination of knowledge
Articles in Press
12/5/2022 6:01:26 PM | Browse: 46 | Download: 121
Publication Name World Journal of Gastroenterology
Manuscript ID 80010
Country/Territory Greece
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Acute liver injury in COVID-19 patients hospitalized in the intensive care unit: Narrative review
Manuscript Source Invited Manuscript
All Author List Effie Polyzogopoulou, Pinelopi Amoiridou, Theodore P Abraham and Ioannis Ventoulis
Funding Agency and Grant Number
Corresponding Author Ioannis Ventoulis, MD, PhD, Assistant Professor, Department of Occupational Therapy, University of Western Macedonia, Keptse Area, Ptolemaida 50200, Greece. iventoulis@uowm.gr
Key Words Liver injury; COVID-19; Intensive care; Pathophysiological mechanisms; Cytokine storm; Multi-organ failure
Core Tip In recent times, coronavirus disease 2019 (COVID-19) pandemic has substantially altered the hitherto existing medical landscape, causing tremendous perturbations among the global scientific community and imposing a disproportionate burden on healthcare systems worldwide. It soon became apparent that COVID-19 affects multiple organ systems, including the liver. Acute liver injury has been progressively identified as a common, yet often under-recognized, complication of COVID-19, especially in the intensive care unit (ICU) setting, resulting in higher mortality rates. This review attempts to elucidate the underlying pathophysiological mechanisms that contribute to the development of acute liver injury in ICU patients with COVID-19, summarize emergent data and propose therapeutic strategies.
Citation Polyzogopoulou E, Amoiridou P, Abraham TP, Ventoulis I. Acute liver injury in COVID-19 patients hospitalized in the intensive care unit: Narrative review. World J Gastroenterol 2022; 28(47): 6662-6688
Received
2022-09-13 22:26
Peer-Review Started
2022-09-13 22:28
To Make the First Decision
Return for Revision
2022-10-19 19:13
Revised
2022-11-14 23:56
Second Decision
2022-12-02 03:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-12-05 18:01
Articles in Press
2022-12-05 18:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-12-06 10:00
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com