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11/23/2022 2:44:19 AM | Browse: 31 | Download: 31
Publication Name World Journal of Gastroenterology
Manuscript ID 80143
Country/Territory China
Category Gastroenterology & Hepatology
Manuscript Type Review
Article Title Alterations of the gut microbiota in coronavirus disease 2019 and its therapeutic potential
Manuscript Source Invited Manuscript
All Author List Hui Xiang and Qi-Ping Liu
Funding Agency and Grant Number
Corresponding Author Hui Xiang, MM, Doctor, Department of Infectious Disease, Chongqing University Three Gorges Hospital, No. 165 Xincheng Road, Chongqing 404100, China. xianghui9312@163.com
Key Words COVID-19; SARS-CoV-2; Angiotensin-converting enzyme 2; Gut microbiota; Dysbiosis; Lung
Core Tip Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global health threat. SARS-CoV-2 infects host cells through binding to angiotensin-converting enzyme 2. COVID-19 patients exhibit gut dysbiosis. Here, the gut microbiota alterations in COVID-19 are summarized. The pathways and possible mechanisms of dysbiosis caused by SARS-CoV-2, as well as the impact of the gut microbiota and its metabolites on the inflammatory response and antiviral effects during the course of the disease are also described. Therefore, targeting the gut microbiota should be considered a promising strategy for COVID-19 prevention, treatment, and prognostic assessment.
Citation Xiang H, Liu QP. Alterations of the gut microbiota in coronavirus disease 2019 and its therapeutic potential. World J Gastroenterol 2022; 28(47): 6689-6701
2022-09-18 11:41
Peer-Review Started
2022-09-18 11:43
To Make the First Decision
Return for Revision
2022-10-30 18:20
2022-11-07 12:21
Second Decision
2022-11-22 03:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-11-23 02:44
Articles in Press
2022-11-23 02:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-11-28 02:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Assistant Editor Assistant Editor
Science Editor Yu-Lu Chen
Reviewer Code 05400886, and 05213310
Editorial Director
Journal Chief Editor
Company Chief Editor Li Ma
Language Editor
Production Editor Yi-Xuan Cai
Responsible Production Editor Yi-Xuan Cai
Responsible Science Editor
Proofing Editorial Director Jin-Lei Wang
Proofing Editor-in-Chief Lian-Sheng Ma