Publication Name	World Journal of Virology
Manuscript ID	80601
Country	Greece

Category	Immunology
Manuscript Type	Minireviews
Article Title	Immune-mediated liver injury following COVID-19 vaccination
Manuscript Source	Invited Manuscript
All Author List	Georgios Schinas, Eleni Polyzou, Vasiliki Dimakopoulou, Stamatia Tsoupra, Charalambos Gogos and Karolina Akinosoglou
Funding Agency and Grant Number
Corresponding Author	Karolina Akinosoglou, MD, PhD, Associate Professor, Department of Internal Medicine, University of Patras, 5th floor, University General Hospital of Patras, Patras 26504, Greece. akin@upatras.gr
Key Words	Adverse effects; COVID-19 vaccines; mRNA vaccine; Autoimmune Hepatitis; Chemical and Drug Induced Liver Injury; Autoimmunity
Core Tip	Following the worldwide implementation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination protocols, several reports suggest an increase in the occurrence of autoimmune phenomena involving the liver. Studies on vaccine-induced liver injury point to a specific pattern of hepatocellular injury that involves immune-mediated pathways. This minireview explores the underlying pathophysiology of immune-mediated liver injury following SARS-CoV-2 vaccination and examines the most widely distributed vaccine formulations’ autoimmune and hepatotoxic potential.
Citation	Schinas G, Polyzou E, Dimakopoulou V, Tsoupra S, Gogos C, Akinosoglou K. Immune-mediated liver injury following COVID-19 vaccination. World J Virol 2023; 12(2): 100-108

Received	2022-10-11 23:48
Peer-Review Started	2022-10-11 23:52
To Make the First Decision
Return for Revision	2022-11-15 20:41
Revised	2022-11-23 16:52
Second Decision	2023-01-18 03:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-01-23 18:26
Articles in Press	2023-01-23 18:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-02-13 05:41

ISSN	2220-3249 (online)
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