| Category |
Research & Experimental Medicine |
| Manuscript Type |
Observational Study |
| Article Title |
Hepatobiliary manifestations following two-stages elective laparoscopic restorative proctocolectomy for patients with ulcerative colitis: A prospective observational study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tamer A A M Habeeb, Abdulzahra Hussain, Mauro Podda, Pasquale Cianci, Bruce Ramshaw, Khaled Safwat, Wesam M Amr, Tamer Wasefy, Alaa A Fiad, Mohamed Ibrahim Mansour, Adel Mahmoud Moursi, Gamal Osman, Anass Qasem, Mohamed Fawzy, Mohamed Ibrahim Abo Alsaad, Abd-Elfattah Kalmoush, Mohammed Shaaban Nassar, Fawzy M Mustafa, Mahmoud Hassib Morsi Badawy, Ahmed Hamdy, Eman Eltokhy, Hamdi Elbelkasi, Bassam Mousa, Abd-Elrahman M Metwalli, Walid A Mawla, Mostafa M Elaidy, Muhammad Ali Baghdadi and Ahmed Raafat |
| Funding Agency and Grant Number |
|
| Corresponding Author |
Tamer A A M Habeeb, MD, Assistant Professor, Department of General Surgery, Faculty of Medicine, Zagazig University, Zagazig 44759, Sharkia, Egypt. tameralnaimy@hotmail.com |
| Key Words |
Courses; Hepatobiliary manifestations; Primary sclerosing cholangitis; Restorative proctocolectomy |
| Core Tip |
There has been little research on the efficacy of proctocolectomy in ulcerative colitis patients with hepatobiliary manifestations. The course of hepatobiliary symptoms after proctocolectomy is being evaluated prospectively in our study. The main finding of this study was that two-thirds of patients had an unchanged course following surgery, whereas 16.8% had a progressive or regressive course. The mortality rate was 6%, and 15% of patients required surgery due to recurrence or worsening symptoms. Most primary sclerosing cholangitis patients (87.5%) had an unchanged course, with only 12.5% progressing. Two-thirds (64.3%) of fatty liver patients progressed, whereas one-third (35.7%) remained stationary. At 12, 24, 36, and 48 mo, the survival rates were 98.8%, 97%, 95.8%, and 94%, respectively. |
| Citation |
Habeeb TAAM, Hussain A, Podda M, Cianci P, Ramshaw B, Safwat K, Amr WM, Wasefy T, Fiad AA, Mansour MI, Moursi AM, Osman G, Qasem A, Fawzy M, Alsaad MIA, Kalmoush A, Nassar MS, Mustafa FM, Badawy MHM, Hamdy A, Elbelkasi H, Mousa B, Metwalli AEM, Mawla WA, Elaidy MM, Baghdadi MA, Raafat A. Hepatobiliary manifestations following two-stages elective laparoscopic restorative proctocolectomy for patients with ulcerative colitis: A prospective observational study. World J Gastrointest Surg 2023; 15(2): 234-248 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
