Publication Name	World Journal of Gastroenterology
Manuscript ID	81411
Country	Australia

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Older adults with acute severe ulcerative colitis have similar steroid non-response and colectomy rates as younger adults
Manuscript Source	Unsolicited Manuscript
All Author List	Deloshaan Subhaharan, Pradeep Kakkadasam Ramaswamy, Laura Willmann, Hadi Moattar, Maneesha Bhullar, Naveed Ishaq, Alexander Dorrington, Dheeraj Shukla, Carolyn McIvor, John Edwards and Waled Mohsen
Funding Agency and Grant Number
Corresponding Author	Deloshaan Subhaharan, MD, Doctor, Department of Digestive Diseases, Gold Coast University Hospital, 1 Hospital Boulevard, Southport, Gold Coast 4215, Queensland, Australia. deloshaan.subhaharan@health.qld.gov.au
Key Words	Elderly; Ulcerative colitis; Acute severe ulcerative colitis; Colectomy; Rescue therapy; Infliximab
Core Tip	This is a retrospective study to assess the outcomes of older adults (≥ 60 years of age) hospitalised with acute severe ulcerative colitis (ASUC) as per Truelove and Witts’ criteria. We identified 45 episodes of ASUC in older adults and compared outcomes with 181 episodes of ASUC in patients < 60 years of age. Older adults with ASUC have similar steroid non-response rate, response to medical rescue therapy and colectomy rates up to 12 mo from index admission, when compared to patients less than 60 years of age.
Citation	Subhaharan D, Ramaswamy PK, Willmann L, Moattar H, Bhullar M, Ishaq N, Dorrington A, Shukla D, McIvor C, Edwards J, Mohsen W. Older adults with acute severe ulcerative colitis have similar steroid non-response and colectomy rates as younger adults. World J Gastroenterol 2023; 29(16): 2469-2478

Received	2022-11-15 00:36
Peer-Review Started	2022-11-15 00:39
To Make the First Decision
Return for Revision	2023-02-02 07:45
Revised	2023-02-11 00:55
Second Decision	2023-03-24 02:57
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-03-24 06:36
Articles in Press	2023-03-24 06:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-03-29 01:00

ISSN	1007-9327 (print) and 2219-2840 (online)
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