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3/17/2023 6:14:33 AM | Browse: 60 | Download: 0
Publication Name World Journal of Stem Cells
Manuscript ID 82676
Country/Territory China
Category Medicine, Research & Experimental
Manuscript Type Minireviews
Article Title Mesenchymal stem/stromal cells-derived exosomes for osteoporosis treatment
Manuscript Source Invited Manuscript
All Author List Kai-Lun Huo, Tie-Yi Yang, Wei-Wei Zhang and Jin Shao
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81703533
Natural Science Foundation of Shanghai 20ZR1449500
Shanghai Jiao Tong University Medical Engineering Cross Fund YG2019GD02
Science Technology Development Fund of Shanghai Pudong New Area PKJ2020-Y28
Medical discipline Construction Project of Pudong Health Committee of Shanghai PWYts2021-05
Corresponding Author Jin Shao, MD, PhD, Associate Professor, Deputy Director, Department of Orthopedics, Pudong New Area Gongli Hospital, School of Medical Technology, University of Shanghai for Science and Technology, No. 219 Miaopu Road, Pudong New Area, Shanghai 200135, China. shaojin_1977@126.com
Key Words Mesenchymal stem cells; Exosome; Osteoporosis; Osteoblasts; Osteoclasts; Bone immunity
Core Tip Osteoporosis is one of the major diseases endangering bone health in the elderly. The existing treatment drugs have problems such as long-term administration and side effects; thus, it is fundamentally difficult to cure osteoporosis. Exosomes derived from mesenchymal stem cells (MSCs) are vesicles that deliver signals and molecules between cells and have shown substantial positive effects in pre-clinical trials. In this review, we summarize the latest progress of MSCs-derived exosomes in the regulation of bone metabolism.
Citation Huo KL, Yang TY, Zhang WW, Shao J. Mesenchymal stem/stromal cells-derived exosomes for osteoporosis treatment. World J Stem Cells 2023; 15(3): 83-89
Received
2022-12-26 07:01
Peer-Review Started
2022-12-26 07:02
To Make the First Decision
Return for Revision
2023-01-03 05:36
Revised
2023-01-17 09:51
Second Decision
2023-03-08 03:08
Accepted by Journal Editor-in-Chief
2023-03-09 15:55
Accepted by Company Editor-in-Chief
2023-03-17 06:14
Articles in Press
2023-03-17 06:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2023-03-20 01:54
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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