Publication Name	World Journal of Pharmacology
Manuscript ID	84146
Country	Brazil

Category	Biochemistry & Molecular Biology
Manuscript Type	Basic Study
Article Title	In silico insight into Amurensinine - an N-Methyl-D-Aspartate receptor antagonist
Manuscript Source	Unsolicited Manuscript
All Author List	Cinthia Façanha Wendel, Queren Hapuque Oliveira Alencar, Rafaela Viana Vieira and Kádima Nayara Teixeira
Funding Agency and Grant Number
Corresponding Author	Kádima Nayara Teixeira, PhD, Professor, Campus Toledo, Universidade Federal do Paraná, Max Planck 3796, Toledo 85.919-899, Paraná, Brazil. kadimateixeira@ufpr.br
Key Words	Amurensinine; Bioinformatics analysis; Isopavines; Molecular docking; N-methyl-D-Aspartate receptor
Core Tip	Amurensinine binds to a region of the amino terminal domain on the N-methyl-D-Aspartate receptor and the interaction is stabilized mainly by covalent bonds, which confer an affinity energy of significant value to the receptor/Ligand complex. The interaction between Amurensinine and the receptor, which is involved in neurological diseases, suggests that this isopavine may interfere with its function, so it may have therapeutic potential in this area.
Citation	Façanha Wendel C, Hapuque Oliveira Alencar Q, Viana Vieira R, Teixeira KN. In silico insight into Amurensinine - an N-Methyl-D-Aspartate receptor antagonist. World J Pharmacol 2023; 12(3): 25-34

Received	2023-03-02 20:04
Peer-Review Started	2023-03-01 18:46
To Make the First Decision
Return for Revision	2023-04-13 08:16
Revised	2023-05-05 21:42
Second Decision	2023-05-31 03:10
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-05-31 07:59
Articles in Press	2023-05-31 07:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-06-14 01:45

ISSN	2220-3192 (online)
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