Publication Name	World Journal of Diabetes
Manuscript ID	85200
Country	Croatia

Category	Endocrinology & Metabolism
Manuscript Type	Observational Study
Article Title	Association between cardiorespiratory fitness level and insulin resistance in adolescents with various obesity categories
Manuscript Source	Invited Manuscript
All Author List	Lavinia La Grasta Sabolic, Marija Pozgaj Sepec, Bernardica Valent Moric and Maja Cigrovski Berkovic
Funding Agency and Grant Number
Corresponding Author	Lavinia La Grasta Sabolic, MD, Postdoctoral Fellow, Department of Pediatric Endocrinology and Diabetology, University Hospital Centre Sestre milosrdnice, 29 Vinogradska, Zagreb 10000, Croatia. lavinia.la.grasta.sabolic@gmail.com
Key Words	Cardiorespiratory fitness; Insulin resistance; Obese adolescents; Severe obesity
Core Tip	The association between obesity and insulin resistance is well established. However, data concerning the relationship between cardiorespiratory fitness (CRF) and insulin resistance in obese adolescents, especially in those with varying obesity categories, are quite limited. The results of present study show that obese adolescents with good CRF have lower homeostatic model assessment of insulin resistance (HOMA-IR) than obese adolescents with poor CRF. Moreover, there is no difference in HOMA-IR between severely obese adolescents with good CRF and mildly obese adolescents with poor CRF. Thus, the improvement of CRF in obese adolescents, including those with severe obesity, should be a therapeutic goal.
Citation	La Grasta Sabolic L, Pozgaj Sepec M, Valent Moric B, Cigrovski Berkovic M. Association between cardiorespiratory fitness level and insulin resistance in adolescents with various obesity categories. World J Diabetes 2023; 14(7): 1126-1136

Received	2023-04-17 08:12
Peer-Review Started	2023-04-17 08:17
To Make the First Decision
Return for Revision	2023-05-15 08:34
Revised	2023-05-22 21:55
Second Decision	2023-06-02 03:11
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-06-02 09:13
Articles in Press	2023-06-02 09:13
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-06-10 20:18
Typeset the Manuscript	2023-07-03 13:51

ISSN	1948-9358 (online)
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