Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	86360
Country	China

Category	Oncology
Manuscript Type	Minireviews
Article Title	Role of inositol polyphosphate-4-phosphatase type II in oncogenesis of digestive system tumors
Manuscript Source	Unsolicited Manuscript
All Author List	Le Han, Shuo Chen and Shi-Yu Du
Funding Agency and Grant Number	Funding Agency Grant Number China-Japan Friendship Hospital Foundation 2019-1-QN-2
Corresponding Author	Shuo Chen, MD, Doctor, Doctor, Department of Gastroenterolog, China-Japan Friendship Hospital, No. 2 East Yinghua Street, Chaoyang District, Beijing 100029, China. 2111210566@bjmu.edu.cn
Key Words	Inositol polyphosphate-4-phosphatase type II; Tumors of the digestive system; Protein kinase B; Serum and glucocorticoid-regulated kinase 3
Core Tip	Inositol polyphosphate-4-phosphatase type II (INPP4B) is a newly discovered PI(3,4,5)P3 phosphatase. This paper reviews studies on the correlations between INPP4B and digestive system tumors and the roles of INPP4B in the development of different tumors to provide a theoretical basis for further research on its molecular mechanism and clinical application. The abnormal expression of INPP4B plays an important role in the development of digestive system tumors. Studies on INPP4B provide new molecular insights for the diagnosis, treatment, and prognosis evaluation of digestive system tumors.
Citation	Han L, Chen S, Du SY. Role of inositol polyphosphate-4-phosphatase type II in oncogenesis of digestive system tumors. World J Gastrointest Oncol 2023; 15(10): 1706-1716

Received	2023-06-13 16:15
Peer-Review Started	2023-06-13 16:15
To Make the First Decision
Return for Revision	2023-07-31 17:03
Revised	2023-08-22 14:59
Second Decision	2023-09-19 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-09-19 07:34
Articles in Press	2023-09-19 07:34
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-09-13 12:54
Typeset the Manuscript	2023-09-27 10:49

ISSN	1948-5204 (online)
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