Publication Name	World Journal of Clinical Cases
Manuscript ID	86679
Country	China

Category	Medicine, General & Internal
Manuscript Type	Retrospective Study
Article Title	Clinical observation of Guipi decoction combined with escieptidine oxalate tablets in patients with depression
Manuscript Source	Unsolicited Manuscript
All Author List	Jia Yu and Feng-Quan Xu
Funding Agency and Grant Number
Corresponding Author	Feng-Quan Xu, MD, Associate Professor, Department of Psychosomatic Medicine, Guang'anmen Hospital, Chinese Academy of Traditional Chinese Medicine, No. 5 Beixiange, Xicheng District, Beijing 100053, China. qazujm1258@163.com
Key Words	Jiajian Guipi decoction; Esiceptidine oxalate tablets; Depressive disorder; Sleep quality; Traditional Chinese medicine syndromes
Core Tip	The combination of Guipi decoction and escieptidine oxalate tablets showed promising clinical benefits for individuals with depression. In a study involving 80 patients, the experimental group receiving both treatments exhibited significantly lower Traditional Chinese medicine (TCM) syndrome scores compared to the control group. Post-treatment, both groups experienced notable reductions in self-rating depression scale and Hamilton depression rating scale scores, with the experimental group showing greater improvement. The total treatment efficiency was significantly higher in the experimental group. Additionally, both groups demonstrated improved sleep quality based on Pittsburgh sleep quality index scores. The experimental group had a lower incidence of adverse reactions compared to the control group. These findings indicate that the combined therapy effectively reduced TCM syndrome scores, improved depressive symptoms, and enhanced sleep quality in patients with depression. Thus, Guipi decoction combined with escieptidine oxalate tablets demonstrates potential as a safe and effective treatment option for depression, warranting further research and consideration in clinical practice.
Citation	Yu J, Xu FQ. Clinical observation of Guipi decoction combined with escieptidine oxalate tablets in patients with depression. World J Clin Cases 2023; 11(29): 7017-7025

Received	2023-07-12 03:42
Peer-Review Started	2023-07-12 03:42
To Make the First Decision
Return for Revision	2023-08-02 09:11
Revised	2023-08-05 09:26
Second Decision	2023-09-18 06:09
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2023-09-18 06:55
Articles in Press	2023-09-18 06:55
Publication Fee Transferred
Edit the Manuscript by Language Editor	2023-09-20 13:10
Typeset the Manuscript	2023-09-28 03:07

ISSN	2307-8960 (online)
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