Publication Name	World Journal of Clinical Cases
Manuscript ID	86977
Country	China

Category	Critical Care Medicine
Manuscript Type	Case Report
Article Title	Emphysematous thrombophlebitis caused by a misplaced central venous catheter: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Ni Chen, Hua-Jun Chen, Tao Chen, Wen Zhang, Xiao-Yun Fu and Zhou-Xiong Xing
Funding Agency and Grant Number	Funding Agency Grant Number Guizhou Science and Technology Department QIANKEHEZHICHEN[2022]YIBAN179 Foundation of Kweichow Moutai Hospital MTyk2022-12 Department of Health of Guizhou Province gzwkj2021-036 Guizhou Education Department QIANJIAOHEKYZI[2018]239
Corresponding Author	Zhou-Xiong Xing, MD, Doctor, Doctor, Department of Critical Care Medicine, The Affiliated Hospital of Zunyi Medical University, No. 149 Dalian Road, Zunyi 563000, Guizhou Province, China. xingzhouxiong111@126.com
Key Words	Emphysematous thrombophlebitis; Septic thrombophlebitis; Central venous catheter; Ultrasound; Catheter-related thrombosis; Central venous catheter-related bloodstream infection; Case report
Core Tip	Central venous catheters (CVCs) often cause life-threatening complications, especially CVC-related bloodstream infection and catheter-related thrombosis. Emphysematous thrombophlebitis is a rare but life-threatening CVC-related bloodstream infection associated with thrombosis and gas formation in the vein. However, timely diagnosis remains a challenge for clinicians. Here, we report an unusual case of misplaced CVC-induced emphysematous thrombophlebitis rapidly diagnosed by point-of-care ultrasound (POCUS). POCUS revealed thrombosis surrounding the misplaced CVC in the right internal jugular vein and gas bubbles manifesting as hyperechoic lines with dirty shadowing and comet-tail artifacts. Knowledge of air-related artifacts may help physicians rapidly diagnose emphysematous thrombophlebitis.
Citation	Chen N, Chen HJ, Chen T, Zhang W, Fu XY, Xing ZX. Emphysematous thrombophlebitis caused by a misplaced central venous catheter: A case report. World J Clin Cases 2023; 11(29): 7207-7213

Received	2023-07-18 08:32
Peer-Review Started	2023-07-18 08:34
To Make the First Decision
Return for Revision	2023-08-09 08:55
Revised	2023-08-22 08:48
Second Decision	2023-09-19 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-09-19 07:26
Articles in Press	2023-09-19 07:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-09-25 07:13

ISSN	2307-8960 (online)
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