Publication Name	World Journal of Clinical Oncology
Manuscript ID	87022
Country	China

Category	Oncology
Manuscript Type	Basic Study
Article Title	Hub genes and their key effects on prognosis of Burkitt lymphoma
Manuscript Source	Unsolicited Manuscript
All Author List	Yan-Feng Xu, Guan-Yun Wang, Ming-Yu Zhang and Ji-Gang Yang
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) 82272034
Corresponding Author	Ji-Gang Yang, MD, PhD, Chief Doctor, Professor, Researcher, Department of Nuclear Medicine, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong An Road, Xicheng District, Beijing 100050, China. yangjigang@ccmu.edu.cn
Key Words	Burkitt lymphoma; Weighted gene co-expression network analysis; Microarray data; Functional enrichment analysis; Prognosis; Therapeutic target
Core Tip	This study represents the pioneering investigation of gene expression in Burkitt lymphoma (BL) using weighted gene co-expression network analysis, coupled with functional enrichment analysis. In this study, we have successfully identified and validated 10 hub genes. Survival analysis has demonstrated that the overexpression of CXCL10 and IL2RA in BL may serve as robust prognostic indicators. Furthermore, an integrated mRNA signature and age nomogram potentially provide valuable prognostic insights for patients with BLs.
Citation	Xu YF, Wang GY, Zhang MY, Yang JG. Hub genes and their key effects on prognosis of Burkitt lymphoma. World J Clin Oncol 2023; 14(10): 357-372

Received	2023-07-19 11:35
Peer-Review Started	2023-07-19 11:37
To Make the First Decision
Return for Revision	2023-08-24 08:10
Revised	2023-09-06 11:32
Second Decision	2023-09-18 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2023-09-18 08:44
Articles in Press	2023-09-18 08:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2023-10-18 10:21

ISSN	2218-4333 (online)
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