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Articles in Press
9/18/2023 6:54:18 AM | Browse: 54 | Download: 0
| Category |
Hematology |
| Manuscript Type |
Observational Study |
| Article Title |
Effect of T-regulatory cells and interleukin-35, interleukin-10, and transforming growth factor-beta on diffuse large B-cell lymphoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hao Wu, Hui-Cong Sun and Gui-Fang Ouyang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Zhejiang TCM Science and Technology Project |
2023ZL653 |
| Zhejiang Medical Science and Technology Plan Project-Clinical Research Application Project A |
2021KY273 |
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| Corresponding Author |
Gui-Fang Ouyang, MD, Chief Physician, Department of Hematology, The First Affiliated Hospital of Ningbo University, No. 59 Liuting Street, Ningbo 315010, Zhejiang Province, China. oyguifangoy@163.com |
| Key Words |
Diffuse large B-cell lymphoma; T-regulatory cells; Interleukin-35; Interleukin-10; Transforming growth factor-beta; Immune response |
| Core Tip |
To study the expression and significance of T-regulatory cells (Tregs) interleukin (IL)-35, IL-10, and transforming growth factor-beta (TGF-β) in diffuse large B-cell lymphoma (DLBCL). Seventy-nine patients were enrolled and divided into three groups according to the evaluation of clinical efficacy: Incipient, effectively treated, and relapsed-refractory. Thirty healthy individuals comprised the control group. The expression of Tregs and their associated factors IL-35, IL-10, and TGF-β in the four groups were analyzed. Finally, we found that Tregs, IL-35, and IL-10 are closely associated with the occurrence and development of DLBCL, which may be helpful in the analysis of disease prognosis. |
| Citation |
Wu H, Sun HC, Ouyang GF. Effect of T-regulatory cells and interleukin-35, interleukin-10, and transforming growth factor-beta on diffuse large B-cell lymphoma. World J Clin Cases 2023; 11(29): 7075-7081 |
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Received |
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2023-08-08 10:35 |
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Peer-Review Started |
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2023-08-04 09:06 |
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To Make the First Decision |
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Return for Revision |
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2023-08-24 07:00 |
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Revised |
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2023-09-08 07:42 |
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Second Decision |
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2023-09-18 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-09-18 06:54 |
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Articles in Press |
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2023-09-18 06:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-09-25 07:13 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
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