Publication Name	World Journal of Psychiatry
Manuscript ID	100112
Country	China

Category	Psychiatry
Manuscript Type	Observational Study
Article Title	Mood symptoms, cognitive function and changes of brain hemodynamics in patients with COVID-19: A functional near-infrared spectroscopy study
Manuscript Source	Unsolicited Manuscript
All Author List	Wen-Jin Ma, Ruo-Chao Yuan, Zi-Yu Peng, Qian Wu, Manal Al-Matary, Hui-Shu Yang, Peng Cheng, Guang-Ju Zhao, Chao-Chao Lu, Yue-Xin Zhang, Jia-Kun Hong and Wei-Hui Li
Funding Agency and Grant Number	Funding Agency Grant Number Hunan Provincial Scientific Research Plan Project of Traditional Chinese Medicine National Natural Science Foundation of China 82371521 Special Tasks for the Construction of Hunan Innovative Province 2023SK4002
Corresponding Author	Wei-Hui Li, MD, PhD, Department of Psychiatry, National Clinical Research Center for Mental Disorders, National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. weihui_li@csu.edu.cn
Key Words	COVID-19; Depression; Anxiety; Cognitive function; Functional near-infrared spectroscopy; Verbal fluency test
Core Tip	Our study provides a kind of evidence that the psychological and emotional issues brought about by coronavirus disease 2019 (COVID-19) are not only due to external social factors but also involve more direct brain neural mechanisms and abnormal neural circuits. In specifically, the COVID-19 infection damages bilateral Broca area and the dorsolateral prefrontal cortex, thus affecting cognitive function and causing mood symptoms. In our study, patients with acute COVID-19 infection were included to rule out the effect of stressors on mood symptoms, and the functional near-infrared spectroscopy data of resting-state and task state confirm each other.
Citation	Ma WJ, Yuan RC, Peng ZY, Wu Q, Al-Matary M, Yang HS, Cheng P, Zhao GJ, Lu CC, Zhang YX, Hong JK, Li WH. Mood symptoms, cognitive function and changes of brain hemodynamics in patients with COVID-19: A functional near-infrared spectroscopy study. World J Psychiatry 2025; In press

Received	2024-08-08 07:39
Peer-Review Started	2024-08-08 07:39
To Make the First Decision
Return for Revision	2024-10-20 11:10
Revised	2024-11-02 19:43
Second Decision	2025-01-10 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-10 07:39
Articles in Press	2025-01-10 07:39
Publication Fee Transferred	2024-12-05 03:17
Edit the Manuscript by Language Editor	2025-01-17 00:30
Typeset the Manuscript

ISSN	2220-3206 (online)
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