Publication Name	World Journal of Nephrology
Manuscript ID	100268
Country	United States

Category	Medicine, General & Internal
Manuscript Type	Review
Article Title	Vitamin B12 deficiency in dialysis patients: risk factors, diagnosis, complications, and treatment: A comprehensive review
Manuscript Source	Unsolicited Manuscript
All Author List	Ghada Araji, Praneeth R Keesari, Varun Chowdhry, Jonathan Valsechi-Diaz, Sarah Afif, Wassim Diab and Suzanne El-Sayegh
Funding Agency and Grant Number
Corresponding Author	Ghada Araji, MD, Doctor, Doctor, Department of Internal Medicine, Northwell Health-Staten Island University Hospital, 475 Seaview Ave, Staten Island, NY 10305, United States. garaji@northwell.edu
Key Words	Vitamin B12 deficiency; Dialysis; Risk factors; Diagnostic challenges; Complications; Treatment
Core Tip	This review highlights the critical yet often overlooked issue of vitamin B12 deficiency in dialysis patients, emphasizing its complex diagnosis and severe complications such as anemia, neuropathy, and cardiovascular risk. The review advocates for a proactive approach in diagnosing and managing vitamin B12 deficiency, recommending comprehensive assessments beyond standard serum levels and highlighting the efficacy of high-dose oral and parenteral supplementation. These insights underscore the necessity for heightened awareness and targeted interventions to improve patient outcomes in this vulnerable population.
Citation	<p>Araji G, Keesari PR, Chowdhry V, Valsechi-Diaz J, Afif S, Diab W, El-Sayegh S. Vitamin B12 deficiency in dialysis patients: risk factors, diagnosis, complications, and treatment: A comprehensive review. <i>World J Nephrol</i> 2024; 13(4): 100268</p>

Received	2024-08-11 22:57
Peer-Review Started	2024-08-11 22:57
To Make the First Decision
Return for Revision	2024-09-20 09:25
Revised	2024-09-24 01:26
Second Decision	2024-10-08 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-10-08 08:38
Articles in Press	2024-10-08 08:38
Publication Fee Transferred	2024-10-16 15:53
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-10-27 01:54

ISSN	2220-6124 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com