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Publication Name World Journal of Psychiatry
Manuscript ID 100289
Country China
Category Psychiatry
Manuscript Type Case Control Study
Article Title Degree centrality values in left calcarine as a potential imaging biomarker for anxious major depressive disorder
Manuscript Source Unsolicited Manuscript
All Author List Yu-Jun Gao, Li-Li Meng, Zhao-Yuan Lu, Xiang-You Li, Ru-Qin Luo, Hang Lin, Zhi-Ming Pan, Bao-Hua Xu, Qian-Kun Huang, Zhi-Gang Xiao, Ting-Ting Li, E Yin, Nian Wei, Chen Liu and Hong Lin
Funding Agency and Grant Number
Funding Agency Grant Number
Hubei Provincial Department of Science and Technology Natural Fund 2024AFC0S6
the Open Fund of the Mental Health Research Institute at Three Gorges University YCXL-23-11
Corresponding Author Yu-Jun Gao, PhD, Department of Psychiatry, Wuhan Wuchang Hospital, No. 505 South Luoshi Road, Hongshan District, Wuhan 430064, Hubei Province, China. gaoyujun19820214@163.com
Key Words Major depressive disorder; Anxiety; Degree centrality; Resting-state functional magnetic resonance imaging
Core Tip In this study, we investigated brain regions with altered degree centrality (DC) values by detecting DC in anxious major depressive disorder (MDD) patients and non-anxious MDD patients, and characterized them as possible neuroimaging biomarkers using receiver operator characteristic analysis. The results of our study showed that DC values of the right fusiform gyrus and bilateral calcarine (CAL) were reduced in the anxious MDD group compared to the non-anxious MDD group. Abnormal DC values in the left CAL may distinguish MDD from its anxiety subtype and serve as a potential neuroimaging biomarker for anxious MDD.
Citation Gao YJ, Meng LL, Lu ZY, Li XY, Luo RQ, Lin H, Pan ZM, Xu BH, Huang QK, Xiao ZG, Li TT, Yin E, Wei N, Liu C, Lin H. Degree centrality values in left calcarine as a potential imaging biomarker for anxious major depressive disorder. World J Psychiatry 2025; In press
Received
2024-08-12 15:32
Peer-Review Started
2024-08-12 15:32
To Make the First Decision
Return for Revision
2024-11-23 10:12
Revised
2024-12-23 15:19
Second Decision
2025-01-23 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-01-23 11:19
Articles in Press
2025-01-23 11:19
Publication Fee Transferred
2024-12-26 01:48
Edit the Manuscript by Language Editor
2025-01-26 10:00
Typeset the Manuscript
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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