Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	100425
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Endoscopic and pathological features of neoplastic transformation of gastric hyperplastic polyps: Retrospective study of 4010 cases
Manuscript Source	Unsolicited Manuscript
All Author List	Dong-Xue Zhang, Zhan-Yue Niu, Ye Wang, Ming Zu, Ya-Han Wu, Yan-Yan Shi, He-Jun Zhang, Jing Zhang and Shi-Gang Ding
Funding Agency and Grant Number
Corresponding Author	Shi-Gang Ding, MD, Chief, Professor, Department of Gastroenterology, Peking University Third Hospital, No. 49 North Garden Road, Haidian District, Beijing 100191, China. dingshigang222@163.com
Key Words	Endoscopy; Gastric hyperplastic polyps; Neoplastic transformation; Pathology; Risk factors; Tumour
Core Tip	Our results show that larger diameter, the presence of multiple polyps, pedunculated or semi-pedunculated shape, and specific background gastric mucosa were risk factors for neoplastic transformation. Furthermore, age > 65 years and male sex were important indicators for predicting the risk of malignant transformation of gastric hyperplastic polyps. Our findings suggest that for polyps with the abovementioned endoscopic and pathological features, clinicians should be alert to the possibility of neoplastic transformation to improve the diagnosis rate of the neoplastic transformation of gastric hyperplastic polyps. Additionally, our study showed that Helicobacter pylori infection was not associated with the risk.
Citation	Zhang DX, Niu ZY, Wang Y, Zu M, Wu YH, Shi YY, Zhang HJ, Zhang J, Ding SG. Endoscopic and pathological features of neoplastic transformation of gastric hyperplastic polyps: Retrospective study of 4010 cases. World J Gastrointest Oncol 2024; In press

Received	2024-08-15 20:05
Peer-Review Started	2024-08-15 20:05
To Make the First Decision
Return for Revision	2024-09-11 07:47
Revised	2024-09-17 15:04
Second Decision	2024-09-29 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-09-29 07:38
Articles in Press	2024-09-29 07:38
Publication Fee Transferred	2024-09-30 02:46
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Typeset the Manuscript

ISSN	1948-5204 (online)
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