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Publication Name World Journal of Clinical Pediatrics
Manuscript ID 100453
Country India
Category Pediatrics
Manuscript Type Prospective Study
Article Title Cardiovascular involvement in multisystem inflammatory syndrome in children and midterm follow-up from a pediatric tertiary center in India
Manuscript Source Invited Manuscript
All Author List Poovazhagi Varadarajan, Ritchie Sharon Solomon, Seenivasan Subramani, Ramesh Subramanian, Gomathy Srividya and Elilarasi Raghunathan
Funding Agency and Grant Number
Corresponding Author Ritchie Sharon Solomon, MD, Assistant Professor, Department of Pediatric Cardiology, Institute of Child Health and Hospital for Children, Madras Medical College, Periyar Salai, Park Town, Chennai 600003, Tamil Nādu, India. ritchie_sharon@yahoo.com
Key Words Multisystem inflammatory syndrome in children; Cardiovascular; Midterm follow-up; Coronary artery aneurysm; Shock; Left ventricular dysfunction
Core Tip Multisystem inflammatory syndrome in children associated with severe acute respiratory syndrome coronavirus can affect the cardiovascular system leading to morbidity and mortality. This prospective study analysed the spectrum of cardiovascular involvement and aimed at determining the associations with clinical and laboratory parameters. Of the 211 patients with cardiac involvement, shock was the predominant finding followed by pericardial effusion, left ventricular (LV) dysfunction, mitral regurgitation and coronary aneurysm. LV function normalized in majority of children within two weeks. Most of the coronary abnormalities normalized within 6 months. None of the laboratory parameter was predictive of cardiac involvement.
Citation Varadarajan P, Solomon RS, Subramani S, Subramanian R, Srividya G, Raghunathan E. Cardiovascular involvement in multisystem inflammatory syndrome in children and midterm follow-up from a pediatric tertiary center in India. World J Clin Pediatr 2024; In press
Received
2024-08-22 06:53
Peer-Review Started
2024-08-16 18:30
To Make the First Decision
Return for Revision
2024-09-19 21:23
Revised
2024-10-02 20:42
Second Decision
2024-10-30 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-10-30 13:54
Articles in Press
2024-10-30 13:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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