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10/29/2024 11:17:13 AM | Browse: 25 | Download: 2
Publication Name World Journal of Hepatology
Manuscript ID 100677
Country China
Category Gastroenterology & Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Evaluation of autoimmune phenomena in patients with nonalcoholic fatty liver disease on the basis of liver pathology
Manuscript Source Unsolicited Manuscript
All Author List Yu-Jin Zhu, Yan Zhang, Yao Rao, Yong Jiang, Yong-Gang Liu, Jian-Zhou Li, Jia-Qi Yuan, Ying Zhao, Wen-Wen Zheng, Lin Ma, Chun-Yan Wang and Jia Li
Funding Agency and Grant Number
Corresponding Author Chun-Yan Wang, MD, Chief Physician, Department of Gastroenterology, Clinical School of the Second People's Hospital, No. 7 Sudi South Road, Nankai District, Tianjin 300110, China. wangchunyan123@tmu.edu.cn
Key Words Nonalcoholic fatty liver disease; Liver pathology; Autoantibody; Autoimmunity; Clinical indicator
Core Tip Based on biopsy results, we divided 104 patients into three groups for a retrospective cohort study to assess the immune phenomena in patients with nonalcoholic fatty liver disease (NAFLD). Final discovery: NAFLD patients were positive for several autoantibodies. ANA is the most common antibody in NAFLD patients. Portal enlargement was the most common alteration. The incidences of limiting plate disruption and small bile duct hyperplasia are high in patients with NAFLD-related cirrhosis. Some patients had hepatocellular rosettes and were positive for antibodies. These findings indicate that autoimmune phenomena may be more pronounced in patients with NAFLD-related cirrhosis.
Citation Zhu YJ, Zhang Y, Rao Y, Jiang Y, Liu YG, Li JZ, Yuan JQ, Zhao Y, Zheng WW, Ma L, Wang CY, Li N. Evaluation of autoimmune phenomena in patients with nonalcoholic fatty liver disease on the basis of liver pathology. World J Hepatol 2024; In press
Received
2024-08-26 05:15
Peer-Review Started
2024-09-06 00:49
To Make the First Decision
Return for Revision
2024-09-25 10:02
Revised
2024-10-14 14:47
Second Decision
2024-10-29 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-10-29 11:17
Articles in Press
2024-10-29 11:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
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