Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	101260
Country	South Korea

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Cohort Study
Article Title	Increased risk of colorectal cancer in young males with higher cardiovascular risk: A nationwide population-based cohort study
Manuscript Source	Unsolicited Manuscript
All Author List	Ji Hyun Song, Su-Yeon Choi, Young Sun Kim, Sun Young Yang and Kyung-Do Han
Funding Agency and Grant Number
Corresponding Author	Young Sun Kim, MD, PhD, Professor, Internal Medicine and Healthcare Research Institute, Seoul National University Hospital Healthcare System Gangnam Center, 39th FL. GFC, Yeoksam dong Gangnam gu, Seoul 06236, South Korea. yspanda@gmail.com
Key Words	Colorectal cancer; Cardiovascular disease; Cohort study; Age; Gender
Core Tip	While studies have reported an association between cardiovascular disease (CVD) and colorectal cancer (CRC), large-scale investigations on the incidence of CRC based on the risk of CVD are lacking. This study benefits from being a nationwide population-based cohort study with long-term follow-up data spanning 10 years, which is a significant strength. This study highlights that increased cardiovascular risk scores are significantly associated with higher CRC risk, especially among males and younger populations. Thus, males with a higher cardiovascular risk score, even at a younger age, are recommended to control their risk factors and undergo individualized CRC screening.
Citation	Song JH, Choi SY, Kim YS, Yang SY, Han KD. Increased risk of colorectal cancer in young males with higher cardiovascular risk: A nationwide population-based cohort stud. World J Gastrointest Oncol 2025; In press

Received	2024-09-09 07:12
Peer-Review Started	2024-09-09 07:12
To Make the First Decision
Return for Revision	2024-11-25 04:07
Revised	2024-12-12 03:41
Second Decision	2025-01-09 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-09 06:37
Articles in Press	2025-01-09 06:37
Publication Fee Transferred	2024-12-31 02:32
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-5204 (online)
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