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Articles in Press
4/14/2025 7:44:50 AM | Browse: 49 | Download: 0
Category |
Biotechnology & Applied Microbiology |
Manuscript Type |
Review |
Article Title |
Understanding the intricate interactions between microbiota and host
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Manuscript Source |
Invited Manuscript |
All Author List |
Aiysha Siddiq Khan, Mohan Kamthan and Asghar Ali |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Indian Council of Medical Research Government of India |
2021-10264/GTGE-BMS |
Department of Health Research, Government of India |
R.12014/61/2022-HR |
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Corresponding Author |
Asghar Ali, PhD, Department of Biochemistry, School of Chemical and Life Sciences, Jamia Hamdard, Hamdard Nagar, New Delhi 110062, Delhi, India. asgharali@jamiahamdard.ac.in |
Key Words |
Gut microbiota; Microbiota-host relationship; Immune system; Faecal microbiome transplantation; Probiotics; Gut dysbiosis; Chronic disorders; Gastrointestinal tract; Metabolic disorders; Gut-organ axis |
Core Tip |
This review article explores the crucial role of gut microbiota and their metabolites in immune regulation, gene expression, and disease progression. It introduces the gut-organ axis hypothesis, linking systemic genetic factors with inflammatory bowel disease progression and treatment response. The study emphasizes microbiota-targeted therapies, such as probiotics, fecal microbiota transplantation, and dietary interventions, as promising strategies in precision medicine. Future research should focus on personalized microbiome-based treatments, leveraging machine learning and advanced analytics to optimize therapies. These insights pave the way for microbiome-driven interventions, revolutionizing treatments for inflammatory bowel disease, autoimmune diseases, and cancer. |
Citation |
Khan AS, Kamthan M, Ali A. Understanding the intricate interactions between microbiota and host. World J Exp Med 2025; In press |
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Received |
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2024-09-11 04:01 |
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Peer-Review Started |
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2024-09-14 03:02 |
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To Make the First Decision |
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Return for Revision |
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2025-02-13 03:05 |
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Revised |
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2025-02-26 17:03 |
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Second Decision |
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2025-04-14 02:41 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-04-14 07:44 |
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Articles in Press |
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2025-04-14 07:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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ISSN |
2220-315x (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
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