Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	101284
Country	United States

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Discordance between endoscopic and histopathologic assessment in ileal Crohn’s disease
Manuscript Source	Unsolicited Manuscript
All Author List	Scott D Lee, Brian Mau, Cody J Avalos, Kindra D Clark-Snustad, Kendra J Kamp and Xianyong Gui
Funding Agency and Grant Number
Corresponding Author	Xianyong Gui, MD, Professor, Department of Pathology, Wake Forest University School of Medicine Bowman Gray Center for Medical Education, 475 Vine Street, Winston-Salem, NC 27101, United States. xgui@wakehealth.edu
Key Words	Crohn’s disease; Endoscopy; Histology; Discordance, Biopsy
Core Tip	Discordance exists between endoscopic and histologic assessments for mucosal inflammation in patients with active ileal Crohn’s disease (CD), even in biopsies targeted at an ulcer edge, while a higher concordance is seen in patients with no endoscopic disease activity. Microscopic patchiness of mucosal inflammation in CD likely contributes to the discrepancy. Given the discordance, ulcer and erosion should not be included in the histologic evaluation scheme for CD.
Citation	<p>Lee SD, Mau B, Avalos CJ, Clark-Snustad KD, Kamp KJ, Gui X. Discordance between endoscopic and histopathologic assessment in ileal Crohn’s disease. <i>World J Gastrointest Endosc</i> 2025; 17(2): 101284</p>

Received	2024-09-09 22:10
Peer-Review Started	2024-09-09 22:10
To Make the First Decision
Return for Revision	2024-09-30 15:09
Revised	2024-10-14 20:28
Second Decision	2024-11-05 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-11-05 10:48
Articles in Press	2024-11-05 10:48
Publication Fee Transferred	2024-12-16 20:05
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-20 02:25

ISSN	1948-5190 (online)
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