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Publication Name World Journal of Transplantation
Manuscript ID 101518
Country United States
Category Transplantation
Manuscript Type Retrospective Study
Article Title Implementation of an opioid-sparing protocol utilizing liposomal bupivacaine and intravenous ketorolac for pain management after living kidney donation
Manuscript Source Invited Manuscript
All Author List Kevin Ly, Antonio Di Carlo, Sunil S Karhadkar, Kenneth Chavin, Francesca Graziano, Kelley Maberry, Nicole Sifontis, Daohai Yu, Xiaoning Lu and Adam Diamond
Funding Agency and Grant Number
Corresponding Author Kevin Ly, PharmD, Department of Pharmacy, Temple University Hospital, 3401 N. Broad Street, Philadelphia, PA 19140, United States. kevin.ly@tuhs.temple.edu
Key Words Opioid; Pain management; Bupivacaine; Ketorolac; Nephrectomy; Living Donation; Renal transplant
Core Tip Opioids are commonly used for management of post-operative pain in living kidney donors. Reducing exposure to opioids is desirable to minimize risk of dependence and potential side effects such as nausea, vomiting, and constipation which may delay discharge. Liposomal bupivacaine, ketorolac, and scheduled acetaminophen have all demonstrated efficacy for management of post-operative pain in this population. The purpose of this retrospective chart review study is to assess the efficacy and safety of an opioid-sparing protocol utilizing a multimodal pain management approach in living kidney donors post-nephrectomy.
Citation Ly K, Di Carlo A, Karhadkar SS, Chavin K, Graziano F, Maberry K, Sifontis N, Yu D, Lu X, Diamond A. Implementation of an opioid-sparing protocol utilizing liposomal bupivacaine and intravenous ketorolac for pain management after living kidney donation. World J Transplant 2025; In press
Received
2024-09-17 13:35
Peer-Review Started
2024-09-17 13:35
To Make the First Decision
Return for Revision
2025-02-11 09:15
Revised
2025-02-23 13:40
Second Decision
2025-03-11 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-03-12 01:38
Articles in Press
2025-03-12 01:38
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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