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Publication Name World Journal of Hepatology
Manuscript ID 101741
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Clinical features and prognosis of drug-induced liver injury in patients with non-alcoholic fatty liver
Manuscript Source Unsolicited Manuscript
All Author List Ying Zhao, Jian-Zhou Li, Yong-Gang Liu, Yu-Jin Zhu, Yan Zhang, Wen-Wen Zheng, Lin Ma, Jia Li and Chun-Yan Wang
Funding Agency and Grant Number
Corresponding Author Chun-Yan Wang, MD, Department of Gastroenterology, Tianjin Second People's Hospital, No. 7 Sudi South Road, Nankai District, Tianjin 300110, China. wangchunyan123@tmu.edu.cn
Key Words Drug-induced liver injury; Nonalcoholic fatty liver; Clinical characteristics; Prognosis; Retrospective study
Core Tip In this retrospective study, we explored the clinical features and prognosis of patients with drug-induced liver injury (DILI) in the setting of nonalcoholic fatty liver (NAFL). We recruited a total of 199 patients diagnosed with DILI by clinical and biochemical indicators. The number of patients diagnosed with NAFL by pathologic biopsy, ultrasound, and computed tomography was 110, and the number of patients without NAFL was 89. DILI resulting from NAFL had more pronounced metabolic index abnormalities, was more prone to cholestasis, had a greater degree of hepatic injury, had a longer recovery time, and may involve more pronounced immunologic factors.
Citation <p>Zhao Y, Li JZ, Liu YG, Zhu YJ, Zhang Y, Zheng WW, Ma L, Li J, Wang CY. Clinical features and prognosis of drug-induced liver injury in patients with non-alcoholic fatty liver. <i>World J Hepatol</i> 2025; 17(2): 101741</p>
Received
2024-09-25 05:16
Peer-Review Started
2024-09-25 05:16
To Make the First Decision
Return for Revision
2024-11-10 14:39
Revised
2024-11-28 03:59
Second Decision
2024-12-25 02:48
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-12-25 11:55
Articles in Press
2024-12-25 11:55
Publication Fee Transferred
2024-12-03 10:35
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-10 07:09
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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