Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	102174
Country	China

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Rare large sigmoid hamartomatous polyp in an elderly patient with atypical Peutz-Jeghers syndrome: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Zhe-Sen Tian, Xiao-Peng Ma, Hong-Xun Ruan, Yang Yang and Ya-Lei Zhao
Funding Agency and Grant Number	Funding Agency Grant Number Medical Science Research Program of Hebei Province 20250060
Corresponding Author	Ya-Lei Zhao, MD, Professor, Department of Anus and Intestine Surgery, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang 050000, Hebei Province, China. doctor_zhaoyalei@163.com
Key Words	Peutz-jeghers syndrome; Sigmoid colon; Large isolated colonic polyp; Skin pigmentation; Case report
Core Tip	Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant hereditary illness defined by the connection of intestinal polyposis, mucosal skin pigmentation, and cancer risk. Due to the older age, the clinical features of mucosal hyperpigmentation were atypia in this case study. Due to the location of the polyp in the sigmoid colon, the common intussusception symptoms of PJS cases in the past did not appear, and only hematochesis and abdominal pain related symptoms were observed. PJS mainly occurs in children and adolescents, often with multiple small intestinal polyps. Such an advanced age with a rare polyp location has not been reported.
Citation	Tian ZS, Ma XP, Ruan HX, Yang Y, Zhao YL. Rare large sigmoid hamartomatous polyp in an elderly patient with atypical Peutz-Jeghers syndrome: A case report. World J Gastrointest Surg 2025; In press

Received	2024-10-10 17:29
Peer-Review Started	2024-10-10 17:29
To Make the First Decision
Return for Revision	2024-12-05 09:50
Revised	2024-12-17 11:40
Second Decision	2025-01-09 02:43
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-09 06:49
Articles in Press	2025-01-09 06:49
Publication Fee Transferred	2024-12-18 06:08
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Typeset the Manuscript

ISSN	1948-9366 (online)
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