| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Lymph node metastatic patterns of gastric carcinoma with a combination of adenocarcinoma and neuroendocrine carcinoma components
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kai Zhou, Zhong-Wu Li, Yan Wu, Zhi-Jie Wang, Ling-Qian Wang, Li-Xin Zhou, Ling Jia, Ke Ji, Xue-Song Yang, Ji Zhang, Xiao-Jiang Wu, An-Qiang Wang and Zhao-De Bu |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Research and Development Program of China |
No. 2023YFF1204702 |
| National Natural Science Foundation of China |
No. 82173151 |
| Capital’s Funds for Health Improvement and Research |
No. CFH 2022-4-1025 |
| Beijing Hospitals Authority Clinical Medicine Development of Special Funding |
No. XMLX202119 |
| Science Foundation of Peking University Cancer Hospital |
No. PY202329 |
|
| Corresponding Author |
Zhao-De Bu, PhD, Professor, Department of Gastrointestinal Surgery, Peking University Cancer Hospital and Institute, No. 52 Fucheng Road, Haidian District, Beijing 100142, China. buzhaode@cjcrcn.org |
| Key Words |
Gastric mixed-adenoneuroendocrine carcinoma; Lymph node metastatic patteren; Clinicopathological features; Adjuvant chemotherapy regimens; Prognosis |
| Core Tip |
Rare individual studies on the lymph node metastasis components and treatment issues of adenoneuroendocrine mixed gastric cancer (G-ANEC). For G-ANEC, even if the neuroendocrine carcinoma (NEC) or adenocarcinoma (AC) component is relatively small in the primary lesion, it may still metastasize to the lymph nodes (LNs). If the metastasis in the LNs consists only of AC components, treatment of G-ANEC should primarily be based on fluoropyrimidine drugs. If the metastasis in the LNs includes NEC components, treatment should primarily be based on the etoposide and cisplatin/irinotecan and cisplatin regimen. |
| Citation |
Zhou K, Li ZW, Wu Y, Wang ZJ, Wang LQ, Zhou LX, Jia L, Ji K, Yang XS, Zhang J, Wu XJ, Wang AQ, Bu ZD. Lymph node metastatic patterns of gastric carcinoma with a combination of adenocarcinoma and neuroendocrine carcinoma components. World J Gastroenterol 2025; 31(8): 102347 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
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|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
