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Publication Name World Journal of Psychiatry
Manuscript ID 102598
Country South Korea
Category Psychiatry
Manuscript Type Letter to the Editor
Article Title Neutrophil gelatinase-associated lipocalin as a biomarker for neuropsychiatric complications in acute ischemic stroke
Manuscript Source Unsolicited Manuscript
All Author List Uchenna E Okpete and Haewon Byeon
Funding Agency and Grant Number
Funding Agency Grant Number
Basic Science Research Program through the National Research Foundation of Korea Funded by the Ministry of Education No. RS-2023-00237287
Regional Innovation Strategy Through the National Research Foundation of Korea Funded by the Ministry of Education No. 2021RIS-003
Corresponding Author Haewon Byeon, Associate Professor, PhD, Department of Digital Anti-aging Healthcare (BK21), Inje University, No. 197 Injero, Gimhae 50834, South Korea. bhwpuma@naver.com
Key Words Acute ischemic stroke; Neutrophil gelatinase-associated lipocalin; Neuropsychiatric complications; Cognitive impairment; Neuroinflammation; Anxiety; Depression; Biomarkers
Core Tip This study investigates neutrophil gelatinase-associated lipocalin (NGAL) as a potential biomarker for neuropsychiatric complications in patients with acute ischemic stroke. Gu et al demonstrate that elevated NGAL levels at admission are associated with a higher risk of cognitive impairment, anxiety, and depression. These findings are significant because such conditions, often overlooked, substantially impact post-stroke recovery and quality of life. This research broadens the understanding of NGAL’s functions beyond its established role as a biomarker for early kidney injury, emphasizing its relevance in neuroinflammation and neuropsychiatric processes.
Citation <p>Okpete UE, Byeon H. Neutrophil gelatinase-associated lipocalin as a biomarker for neuropsychiatric complications in acute ischemic stroke. <i>World J Psychiatry</i> 2025; 15(2): 102598</p>
Received
2024-10-23 02:54
Peer-Review Started
2024-10-23 02:54
To Make the First Decision
Return for Revision
2024-12-05 09:59
Revised
2024-12-17 07:38
Second Decision
2024-12-23 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-12-23 09:08
Articles in Press
2024-12-23 09:08
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-01-06 01:57
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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