Publication Name	World Journal of Stem Cells
Manuscript ID	102923
Country	China

Category	Cell Biology
Manuscript Type	Editorial
Article Title	Mechanisms and challenges of mesenchymal stem cells in the treatment of knee osteoarthritis
Manuscript Source	Invited Manuscript
All Author List	Jing-Shun Lu, Chen-Yu Song, Wen-Jing Cheng and Kai-Yang Wang
Funding Agency and Grant Number
Corresponding Author	Kai-Yang Wang, Assistant Professor, MD, Department of Orthopedic Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, No. 600 Yishan Road, Shanghai 200233, China. ortho_wang@163.com
Key Words	Mesenchymal stem cells; Knee osteoarthritis; Inflammation; Exosome; Biological materials
Core Tip	Mesenchymal stem cells (MSCs) exhibit remarkable efficacy in the field of regenerative medicine and are considered to be the key cells for the repair and regeneration of cartilage. In this paper, we explore the clinical application of MSCs in the treatment mechanism of osteoarthritis and address the challenges associated with MSC therapy.
Citation	<p>Lu JS, Song CY, Cheng WJ, Wang KY. Mechanisms and challenges of mesenchymal stem cells in the treatment of knee osteoarthritis. <i>World J Stem Cells</i> 2025; 17(4): 102923</p>

Received	2024-11-04 12:06
Peer-Review Started	2024-11-04 12:07
To Make the First Decision
Return for Revision	2025-02-10 08:42
Revised	2025-02-22 22:50
Second Decision	2025-03-21 03:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-21 10:23
Articles in Press	2025-03-21 10:23
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-03-27 05:00
Typeset the Manuscript	2025-04-11 06:07

ISSN	1948-0210 (online)
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