| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Predictive model and prognostic insights into duodenal stump fistula following radical gastrectomy with Roux-en-Y reconstruction for gastric cancer
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yang Yu, Suguru Yamauchi, Sanae Kaji, Yukinori Yube, Motomi Nasu, Yutaro Yoshimoto, Ming Cheng, Asako Ozaki, Takehiro Watanabe, Hajime Orita, Kaitlyn Ecoff, Shuko Nojiri, Shinji Mine, Yong-You Wu and Tetsu Fukunaga |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| China Scholarship Council Fund |
No. 202308050094 |
|
| Corresponding Author |
Tetsu Fukunaga, Chief Physician, MD, PhD, Professor, Department of Esophageal and Gastroenterological Surgery, Juntendo University, 2-1-1 Hongo Bunkyo Ward, Tokyo 113-8431, Japan. t2fukunaga@gmail.com |
| Key Words |
Gastric cancer; Duodenal stump fistula; Roux-en-Y reconstruction; Predictive nomogram; Cancer survival |
| Core Tip |
This retrospective cohort study included 325 patients who underwent radical gastrectomy with Roux-en-Y reconstruction to identify risk factors for duodenal stump fistula (DSF). Age and obstructive ventilatory failure were identified as independent risk factors for DSF. A nomogram incorporating these risk factors demonstrated robust predictive performance for DSF. DSF significantly affected cancer-specific survival. Suturing fixation of the duodenal stump to the jejunal wall has shown potential as an effective strategy for preventing DSF. |
| Citation |
Yu Y, Yamauchi S, Kaji S, Yube Y, Nasu M, Yoshimoto Y, Cheng M, Ozaki A, Watanabe T, Orita H, Ecoff K, Nojiri S, Mine S, Wu YY, Fukunaga T. Predictive model and prognostic insights into duodenal stump fistula following radical gastrectomy with Roux-en-Y reconstruction for gastric cancer. World J Gastrointest Surg 2025; In press |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
