Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	104505
Country	China

Category	Pathology
Manuscript Type	Retrospective Study
Article Title	Relationship between prognosis and glucose transporter-1 and Ki-67 expression in obstructive colon cancer pre and post stent placement
Manuscript Source	Unsolicited Manuscript
All Author List	Kun-Ning Zhang, Mu-Lan Jin and Zhi-Wei Zhai
Funding Agency and Grant Number
Corresponding Author	Zhi-Wei Zhai, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing 100020, China. zhiweizhai@ccmu.edu.cn
Key Words	Colorectal cancer; Obstruction; Self-expandable metallic stent; Glucose transporter-1; Ki-67
Core Tip	Self-expanding metallic stent placement is becoming a more common treatment approach for obstructive left-sided colon cancer, there is still ongoing debate regarding its long-term impact on patient prognosis. Stent expansion can result in the compression of blood vessels within the tumor due to mechanical pressure, may induce changes in the tumor microenvironment, potentially affecting patient prognosis. Our study found an increase in glucose transporter-1 (GLUT-1) expression in tumor tissues after self-expanding metallic stent placement. Tumor GLUT-1 serves as a prognostic biomarker for the survival of patients with obstructive colon cancer treated with self-expanding metallic stent placement.
Citation	Zhang KN, Jin ML, Zhai ZW. Relationship between prognosis and glucose transporter-1 and Ki-67 expression in obstructive colon cancer pre and post stent placement. World J Gastrointest Surg 2025; In press

Received	2024-12-27 13:38
Peer-Review Started	2024-12-30 01:38
To Make the First Decision
Return for Revision	2025-04-09 12:11
Revised	2025-04-21 15:23
Second Decision	2025-05-14 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-05-14 06:35
Articles in Press	2025-05-14 06:35
Publication Fee Transferred	2025-04-23 13:10
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1948-9366 (online)
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