Publication Name	World Journal of Diabetes
Manuscript ID	104512
Country	China

Category	Pharmacology & Pharmacy
Manuscript Type	Basic Study
Article Title	Examining gut microbiota and metabolites to clarify mechanisms of Dimocarpus longan Lour leaf components against type 2 diabetes
Manuscript Source	Unsolicited Manuscript
All Author List	Piao-Xue Zheng, Chun-Lian Lu, Yan-Li Liang, Yu-Ming Ma, Jia-Wen Peng, Jing-Jing Xie, Jia-Li Wei, Si-Si Chen, Zhi-Dong Ma, Hua Zhu and Jie Liang
Funding Agency and Grant Number	Funding Agency Grant Number the National Natural Science Foundation of China 82160771 NATCM's Project of High-Level Construction of Key TCM Disciplines: Traditional Medicine of Chinese Minority (Zhuang Medicine) zyyzdxk-2023165 Guangxi One Thousand Young and Middle-Aged College and University Backbones Teachers Cultivation Program [2019]5 Guangxi Traditional Chinese Medicine Multidisciplinary Cross Innovation Team Project GZKJ2309 Guangxi Key R&D Plan Project AB21196016 Guangxi Key Discipline of Traditional Chinese Medicine Zhuang Pharmacy GZXK-Z-20-64 The First-Class Subject of Traditional Chinese Medicine (Ethnic Pharmacy) in Guangxi [2018]12 Guangxi Science and Technology Base and Talent Special Project AD20238058 and AD21238031 Third Batch of Cultivating High-level Talent Teams in the “Qi Huang Project” of the Guangxi University of Chinese Medicine 202406 Huang Danian Style Teacher Team From Universities in Guangxi Zhuang Autonomous Region “Traditional Chinese Medicine Inheritance and Innovation Teacher Team” [2023]31
Corresponding Author	Jie Liang, PhD, Professor, College of Pharmacy, Guangxi University of Chinese Medicine, No. 13 Wuhe Avenue, Qingxiu District, Nanning 530200, Guangxi Zhuang Autonomous Region, China. liangj2004@gxtcmu.edu.cn
Key Words	Dimocarpus longan Lour leaf components; Type 2 diabetes; 16S rDNA sequencing; Short-chain fatty acids; Metabolomics
Core Tip	This study investigated the anti-type 2 diabetes mechanism of Dimocarpus longan Lour leaf components (DLC). Results showed that DLC modulated intestinal flora, short-chain fatty acids, and fecal metabolites. It might exert hypoglycemic effects via the gut microbiota-metabolite-host axis, offering new insights for diabetes treatment.
Citation	Zheng PX, Lu CL, Liang YL, Ma YM, Peng JW, Xie JJ, Wei JL, Chen SS, Ma ZD, Zhu H, Liang J. Examining gut microbiota and metabolites to clarify mechanisms of Dimocarpus longan Lour leaf components against type 2 diabetes. World J Diabetes 2025; In press

Received	2024-12-24 08:19
Peer-Review Started	2024-12-27 09:26
To Make the First Decision
Return for Revision	2025-02-13 01:57
Revised	2025-03-10 10:47
Second Decision	2025-06-05 06:44
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-12 03:32
Articles in Press	2025-06-12 03:32
Publication Fee Transferred	2025-04-03 05:15
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Typeset the Manuscript

ISSN	1948-9358 (online)
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