Publication Name	World Journal of Diabetes
Manuscript ID	104576
Country	Taiwan

Category	Endocrinology & Metabolism
Manuscript Type	Observational Study
Article Title	Risks of liver cirrhosis, hepatocellular carcinoma, hepatic-related complications, and mortality in patients with type 2 diabetes in Taiwan
Manuscript Source	Unsolicited Manuscript
All Author List	Hua-Fen Chen, Yung-Yueh Chang, Peter Chen, Xiao-Han Shen, Chin-Huan Chang and Wan-Lun Hsu
Funding Agency and Grant Number	Funding Agency Grant Number Far Eastern Memorial Hospital FEMH-2023-C-082 Far Eastern Memorial Hospital FEMH-2022-C-015 Far Eastern Memorial Hospital FEMH-2022-C-017
Corresponding Author	Hua-Fen Chen, Assistant Professor, Chief, MD, Department of Endocrinology, Far Eastern Memorial Hospital, No. 21 Section 2, Nanya S Road, Banqiao District, New Taipei City 220, Taiwan. hfchen@mail.femh.org.tw
Key Words	Type 2 diabetes mellitus; Liver cirrhosis; Hepatocellular carcinoma; Hepatic-related complications; Mortality; Metabolic dysfunction-associated steatotic liver disease; Metabolic dysfunction-associated steatohepatitis
Core Tip	Nonalcoholic, hepatitis B and C serologically negative patients with type 2 diabetes, one of the cardiometabolic risk factors for metabolic dysfunction-associated steatotic liver disease, exhibited independently increased risks of cirrhosis of the liver, hepatocellular carcinoma, hepatic-related complications, and mortality, irrespective of age or sex. Coexisting obesity, hypertension, and dyslipidemia worsened this risk, but regular exercise could ameliorate hepatic outcomes even after adjustment for confounders.
Citation	<p>Chen HF, Chang YY, Chen P, Shen XH, Chang CH, Hsu WL. Risks of liver cirrhosis, hepatocellular carcinoma, hepatic-related complications, and mortality in patients with type 2 diabetes in Taiwan. <i>World J Diabetes</i> 2025; 16(5): 104576</p>

Received	2024-12-25 08:11
Peer-Review Started	2024-12-25 08:11
To Make the First Decision
Return for Revision	2025-02-14 01:44
Revised	2025-02-25 02:50
Second Decision	2025-03-13 07:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-21 08:27
Articles in Press	2025-03-21 08:27
Publication Fee Transferred	2025-02-27 13:23
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-14 02:39

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com