BPG is committed to discovery and dissemination of knowledge
Articles in Press
4/14/2025 5:54:47 AM | Browse: 45 | Download: 0
Publication Name World Journal of Gastroenterology
Manuscript ID 104758
Country China
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Epstein-Barr virus infection is an independent risk factor for surgery in patients with moderate-to-severe ulcerative colitis
Manuscript Source Unsolicited Manuscript
All Author List Hui Zhang, Xi Gu, Wei He, Shu-Liang Zhao and Zhi-Jun Cao
Funding Agency and Grant Number
Funding Agency Grant Number
General Hospital Integrated Guidance Project of Shanghai Municipal Health Commission and Municipal Administration of Traditional Chinese Medicine (Phase I) ZXXT-202210
"Science and Technology Innovation Action Plan" Medical Innovation Research Project of Shanghai Municipal Science and Technology Commission 22Y11907900
Corresponding Author Zhi-Jun Cao, Chief, MD, PhD, Professor, Division of Gastroenterology and Hepatology, Key Laboratory of Gastroenterology and Hepatology, Ministry of Health, Shanghai Institute of Digestive Disease, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 145 Middle Shandong Road, Shanghai 200001, China. caozj_renji@163.com
Key Words Epstein-Barr virus; Cytomegalovirus; Ulcerative colitis; Colectomy; Predictive model
Core Tip This retrospective single-center observational study investigated the effect of Epstein-Barr virus (EBV) infection of the intestinal mucosa on surgical risk in patients with moderate-to-severe ulcerative colitis (UC). Surgical treatment remains necessary for patients refractory to medical therapy or with severe complications in patients with moderate-to-severe UC. Our study determined that EBV infection of the intestinal mucosa is a significant independent risk factor for colectomy in patients with moderate-to-severe UC. In addition, we developed a new nomogram model including EBV infection to help predict colectomy risk in patients with moderate-to-severe UC.
Citation Zhang H, Gu X, He W, Zhao SL, Cao ZJ. Epstein-Barr virus infection is an independent risk factor for surgery in patients with moderate-to-severe ulcerative colitis. World J Gastroenterol 2025; In press
Received
2024-12-31 10:02
Peer-Review Started
2024-12-31 10:02
To Make the First Decision
Return for Revision
2025-03-05 01:18
Revised
2025-03-18 18:01
Second Decision
2025-04-14 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-14 05:54
Articles in Press
2025-04-14 05:54
Publication Fee Transferred
2025-03-24 14:15
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com