Publication Name	World Journal of Clinical Cases
Manuscript ID	104876
Country	Japan

Category	Pathology
Manuscript Type	Case Report
Article Title	Urothelial carcinoma arising in orthotopic ileal neobladder reconstruction: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Miki Murakami, Hirotsugu Noguchi, Ryosuke Matsushita, Shuichi Tatarano, Mari Kirishima, Takashi Tasaki, Ikumi Kitazono, Michiyo Higashi, Hideki Enokida and Akihide Tanimoto
Funding Agency and Grant Number
Corresponding Author	Akihide Tanimoto, MD, PhD, Professor, Department of Pathology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8544, Japan. akit09@m3.kufm.kagoshima-u.ac.jp
Key Words	Bladder cancer; Urothelial carcinoma; Radical cystectomy; Ileal neobladder; Recurrence; Case report
Core Tip	The simultaneous or metachronous occurrence of multifocal tumors in the urinary tract is characteristic of urothelial carcinoma (UC), and many patients experience recurrence post-surgery. However, recurrence of UC in ileal neobladders is extremely rare. Most cases of UC in the ileal neobladder are initially diagnosed as muscle-invasive bladder cancers. In this case, the pathological stage of the resected bladder after neoadjuvant chemotherapy was UC in situ. Patients who have undergone ileal neobladder surgery should be carefully followed up for a long period because the exfoliated tumor cells could “seed and implant” in the bladder and non-urothelial epithelium.
Citation	Murakami M, Noguchi H, Matsushita R, Tatarano S, Kirishima M, Tasaki T, Kitazono I, Higashi M, Enokida H, Tanimoto A. Urothelial carcinoma arising in orthotopic ileal neobladder reconstruction: A case report. World J Clin Cases 2025; In press

Received	2025-01-05 13:32
Peer-Review Started	2025-01-05 13:33
To Make the First Decision
Return for Revision	2025-04-09 09:57
Revised	2025-04-18 03:23
Second Decision	2025-06-04 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-06-04 09:46
Articles in Press	2025-06-04 09:46
Publication Fee Transferred	2025-05-10 01:53
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ISSN	2307-8960 (online)
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