Publication Name	World Journal of Gastroenterology
Manuscript ID	104932
Country	Italy

Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Gastroparesis, a diabetic complication causing further, even serious, complications: How to prevent its worsening?
Manuscript Source	Invited Manuscript
All Author List	Mauro Bortolotti
Funding Agency and Grant Number
Corresponding Author	Mauro Bortolotti, MD, Department of Internal Medicine and Gastroenterology, S Orsola-Malpighi Polyclinic, University of Bologna, Via Massarenti 48, Bologna 40138, Italy. bormau@tin.it
Key Words	Diabetic gastroparesis; Gastroparesis; Gastric emptying; Enteric neuropathy; Pylorospasm; Body surface gastric mapping; Prokinetics; Antiemetics; Neuromodulators; Endoscopic and surgical treatments
Core Tip	Gastroparesis, a diabetic complication with a worsening delay in gastric emptying (GE), responsible of further serious complications, is due to the progressive multifactorial damage of the enteric neurons. It could be discovered early by performing the antral real-time ultrasonography annually, which measures the GE of a semi-solid meal. Furthermore if “the body surface gastric mapping”, evaluating the gastric bioelectric activity, is normal, the cause of GE may be pylorospasm, to be confirmed manometrically. Subsequently, a strict control of glycemia, even with “artificial pancreas” devices, together with prokinetics intake, which counteracts the symptoms and gastric dilatation, must be done, after the correction of a possible pylorospasm.
Citation	Bortolotti M. Gastroparesis, a diabetic complication causing further, even serious, complications: How to prevent its worsening? World J Gastroenterol 2025; In press

Received	2025-01-07 07:30
Peer-Review Started	2025-01-07 07:30
To Make the First Decision
Return for Revision	2025-03-05 01:10
Revised	2025-04-08 10:46
Second Decision	2025-04-29 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-29 06:26
Articles in Press	2025-04-29 06:26
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript

ISSN	1007-9327 (print) and 2219-2840 (online)
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