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4/14/2025 9:33:35 AM | Browse: 51 | Download: 0
Publication Name World Journal of Transplantation
Manuscript ID 104945
Country Bulgaria
Category Gastroenterology & Hepatology
Manuscript Type Field of Vision
Article Title Current perspectives and guidelines on liver transplantation for metastatic colorectal cancer
Manuscript Source Invited Manuscript
All Author List Mirela Stoyanova, Irena Mircheva, Ivan Chulkov, Madlena Karamiteva, Zvezdina Goranova, Viktoria Simeonova, Miroslav Zashev, Tsvetelina Velikova and Milena Peruhova
Funding Agency and Grant Number
Funding Agency Grant Number
the European Union-NextGenerationEU, through the National Recovery and Resilience Plan of the Republic of Bulgaria BG-RRP-2.004-0008
Corresponding Author Miroslav Zashev, Assistant Professor, Chief Physician, MD, Department of General Surgery, Heart and Brain Hospital, Zdrave 1 Str, Burgas 8000, Bulgaria. zashev.md@gmail.com
Key Words Liver transplantation; Colorectal cancer; Colorectal liver metastasis; Transplant oncology
Core Tip It is a well-established fact that more than 40% of patients with colorectal cancer (CRC) develop liver metastasis during the disease course despite all the surveys leading to more suitable systemic treatments, efficient chemotherapy, and surgical resections. liver transplantation (LT) could be a treatment option for patients with unresectable CRC liver metastasis without extrahepatic involvement. The initial assessment and proper selection of suitable patients is mandatory for better outcomes for these patients. It turns out that to be candidates for an LT, patients have to meet strict criteria described in the two prospective studies, SECA-I and SECA-II. Despite the proven benefits of LT for non-resectable colorectal liver metastases, this method is still not widely used worldwide due to a lack of policy and healthcare reforms in many countries.
Citation Stoyanova M, Mircheva I, Chulkov I, Karamiteva M, Goranova Z, Simeonova V, Zashev M, Velikova T, Peruhova M. Current perspectives and guidelines on liver transplantation for metastatic colorectal cancer. World J Transplant 2025; In press
Received
2025-01-07 07:20
Peer-Review Started
2025-01-07 07:21
To Make the First Decision
Return for Revision
2025-02-18 10:19
Revised
2025-03-03 15:30
Second Decision
2025-04-14 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-14 09:33
Articles in Press
2025-04-14 09:33
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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